COMBINOL-E HYDILAR-DM EURODRYL EURODRYL ANGLODRYL ANGLODRYL EXALYN PRO-LIN PABDRYL PABDRYL PABDRYL DIFEN OROLIN-DM OROLIN SIROLINE CIBCOS PULMOFED PULMOFED PULMOFED AMMOFED AMMOFED AMMOFED DIPHEROL DIPHEROL CEFYL-ESF TRIAD PLUS TUSCOLIN-D DIPHOS LOTUS DIHYDRANIL CAROL RENESED RENESED SURFRADINE SURFRADINE SURFRADINE BROLIN DIPHEX DIPHEX ADALIN THEOPHYL THEOPHYL THEOPHYL CHLOROHIST CHLOROHIST KUFRID REXYL ACEFYL COUGH ACEFYL COUGH NUFYLIN ILLCO ALLERSAL APHYLIN COLDRID M-CEFYL NAFRALINE-DM AMONAF COSOME E ZEVIROL ZEVIROL HYBEX DIPHENE COMPOUND DIPHENE COMPOUND DIPHENE COMPOUND COUGH BENYLIN-DM BENATUSS BENADRYL BENADRYL CALADRYL ACELYNE AMINOLIN PRODRYL EXPECT PRODRYL EXPECT ROFLIN DM ROFLIN TEXCOL-DMD TEXCOL EX HYDRYLLIN ANTI FLU HYDRYLLIN ANTI FLU HYDRYLLIN ANTI FLU HYDRYLLIN HYDRYLLIN HYDRYLLIN-DM HYDRYLLIN-DM TORAX-DM TORAX-EX BROXOL BROPHYL D BROXOL-DM PENTALLIN COLDREX-E ADICOS-M ADICOS-M ADICOS ADICOS ADICOS RESPIRATE-DM COFREST WILSONS COUGH SYRUP COFEX KUFGO AKSODRYL BROVENOL DIMINOL DIMINOL BROVENOL DM BROVENOL DM BLOMINOL EXYLLIN ETAPHYLLINE COUGH SYP ACEFIN PLUS LISKODRYLLIN REGODIL REGODIL REGODIL HYDREX COFSYL BRONCHOSAFE DM BRONIL BRONIL BRONDYL BRONDYL PLUSCODIN COUGH PLUSCODIN COUGH STANDRYLLIN SAPRYLLIN AVALLIN EROCOF-D EROCOF-D CODAMINE DIATONE CHESTYCOF DAGNUM COUGH AMIDILLLIN ASTHMATIC COFBAN-E AM-PHYLLINE GERILINE DIPHENHYDRAMINE SCOTS EXPECTORANT PROLIN BL COF COFLLIN BIOLLIN DM XATUS D XATUS D XATUS ZEOHYDRAMINE ZEOHYDRAMINE ZEOHYDRAMINE AMPHIDRYL NICOR SOLOREX MUCOPHYLLINE DM DIALON KUFMED DRYGLIT SOLUTASSIN NOCOF BRETHONIL BRETHONIL ASTHA MAC SYMEN SYMEN SYMEN AMDIAPAC CHILCOL KAFOLLINE KUFLIN COUGHMED COUGHMED DM COUGHMED DM D-HYDRI BELINKTUS BELINKTUS DM WYDRYLIN DM WYDRYLIN

Dose: 25 mg
Single Dose: 25 (25)
Frequency: 8 hourly
Route: PO
Instructions: Initial, with a double dose at night

Dose: 1.25 to 2.5 mg/kg
Single Dose: 1.9 (1.875)
Frequency: 8 hourly
Route: Oral
Instructions:

Diphenhydramine Hcl is the derivative of Diphenhydramine. It is of Synthetic origin and belongs to Benzoalkylamine. It belongs to H1-antagonist pharmacological group on the basis of mechanism of action and also classified in sedative pharmacological group.The Molecular Weight of Diphenhydramine is 291.80. It is weakly acidic drug, 5.70% solution of the drug is isotonic and Its pKa is 9.0.

Diphenhydramine is contraindicated in conditions like Glucoma,Urinary retention.

The signs and symptoms that are produced after the acute overdosage of Diphenhydramine include Flushing, Nausea, Tachycardia, Convulsions, Coma, Drowsiness, Dry mouth, Urinary retention, Hallucinations, Fever, Ataxia, Headache.The symptomatic adverse reactions produced by Diphenhydramine are more or less tolerable and if they become severe, they can be treated symptomatically, these include Dizziness, Tiredness, Fatigue, Ataxia, Tremors, Nervousness, Tinnitus, Blurred vision, Sedation, Diplopia, Nausea and vomiting, Dermatitis, Euphoria, Epigastric pain, nervousness, Nervousness, dizziness, Ataxia.

Diphenhydramine is primarily indicated in conditions like Anaphylactic reactions, Angioneurotic edema, Antiemetic poisoning, Conjuctivitis, Cough, Menieres disease, Motion sickness, Parkinsonism, Perennial rhinitis, Pruritus, Seasonal rhinitis, Urticaria, Vasomotor rhinitis, and can also be given in adjunctive therapy as an alternative drug of choice in Extrapyramidal disorders, Nausea and vomiting, Vertigo.

Diphenhydramine is known to interact with other drugs, the details of drug interactions is as follows:DrugDetailsSeverityOnsetManagementAlcoholAmphotericin BAtomoxetine HClThe effect and toxicity of atomoxetine could be increased by CYP2D6 inhibitor.Atropine (Sulphate)Cephalothin (Na)Cephalothin (Na) can percipate the drug. It inhibits cyp 2D6 enzyme.Metoprolol (Tartrate)NabiloneConcurrent use may increase the efficacy of nabilone.Concurrent use should be avoided, or you may need dosage adjustments or special tests during treatment.OxymorphoneCentral nervous system- and/or respiratory-depressant effects may be additively or synergistically increased in patients taking multiple drugs that cause these effects, especially in elderly or debilitated patients.ModerateDuring concomitant use of these drugs, patients should be monitored for potentially excessive or prolonged CNS and respiratory depression. Ambulatory patients should be made aware of the possibility of additive CNS effects (e.g., drowsiness, dizziness, lightheadedness, confusion) and counseled to avoid activities requiring mental alertness until they know how these agents affect them. Patients should also be advised to notify their physician if they experience excessive or prolonged CNS effects that interfere with their normal activities.PericyazineThese drugs shouldnot be taken concurrently without doctors prescription.PhenobarbitoneRizatriptanConcurrent use may increase drowsiness.Venlafaxine (HCl) These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

Wheal formation in Skin Sensitizing Test. Determination of plasma theophylline levels by radioimmunoassay.

Drug should not be given to Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.

Elixir Store Below 40°C. Do not Freeze. Protect from Sunlight, Moisture and Heat. Tab, Caps, Cream Store Below 40°C. Protect from Sunlight, Moisture and Heat.

Diphenhydramine should be used with caution in bone marrow depression. Patients should observe caution while driving or performing other task requiring alertness because it may cause drowsiness. It should be used with caution in patients with urinary retention, history of bronchial asthma, hyperthyroidism, cardiovascular or liver disease. It should be used with caution in person with acute or chronic respiratory impairment, especially in children. Do not administer subcutaneously because irritation or lesion may occur. Care should be given in pregnancy.