Dihydrocodeine (Tartrate)

Dihydrocodeine is a mild narcotic analgesic and antitussive, also called as drocode. Chemically Dihydrocodeine (Tartrate) is identified as 4, 5a-epoxy-3-methoxy-17-methylmorphinan-6a-ol. Dihydrocodeine (Tartrate) is effective to relieve moderate to severe pain and swelling.


Brands
Adult Dose
Dose: 0.286 to 0.857 mg/kg
Single Dose: 0.57 (0.5715)
Frequency: 4 hourly
Route: PO
Instructions: As Required
Neonatal
Paedriatic
Dose: 0.4 to 1.2 mg/kg
Single Dose: 0.8 (0.8)
Frequency: 6 hourly
Route: Oral
Instructions: Recommended for 5-12 Yrs of Children
Characteristics
. It is of Synthetic origin and belongs to Opioid. It belongs to OPIATE agonist pharmacological group on the basis of mechanism of action and also classified in Analgesic pharmacological group.The Molecular Weight of Dihydrocodeine (Tartrate) is 451.50. It is strongly acidic drug and Its pKa is 8.8.
Contraindications
Dihydrocodeine (Tartrate) is contraindicated in conditions like Respiratory failure,Bronchospasm,Productive cough,Hepatic failure.
Effects
The severe or irreversible adverse effects of Dihydrocodeine (Tartrate), which give rise to further complications include Dependence.Dihydrocodeine (Tartrate) produces potentially life-threatening effects which include Bronchospasm, Bronchospasm. which are responsible for the discontinuation of Dihydrocodeine (Tartrate) therapy.The signs and symptoms that are produced after the acute overdosage of Dihydrocodeine (Tartrate) include Hypotension, Unconsciousness, Miosis, Depression, Myoclonic twitching, Hypoventilation.The symptomatic adverse reactions produced by Dihydrocodeine (Tartrate) are more or less tolerable and if they become severe, they can be treated symptomatically, these include Dizziness, Nausea, Vomiting, Constipation, Sedation, Hallucination, Euphoria, dizziness.
Indications
Dihydrocodeine (Tartrate) is primarily indicated in conditions like Cough, Diarrhoea, Moderate to severe pain.
Interactions
No data regarding the interactions of Dihydrocodeine (Tartrate) was found.
Interfrence
Risks
Drug should not be given to Paediatrics, Pregnant Mothers, Geriatrics, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
Caps Store Below 40°C. Protect from Sunlight and Moisture.
Warnings
Dihydrocodeine should be used with caution in patients with diseases of the kidney, liver or heart, asthma or other breathing problems, stomach ulcers, bleeding disorders, high blood pressure, severe diarrhea, drug dependency and of any drug allergy. It should be used with caution while driving or engaging in activities requiring alertness. Limit alcohol consumption because it may add to the dizziness or drowsiness effects of this drug, heavy drinking of alcohol may make stomach and intestines more susceptible to the irritating effects of this medication increasing the risk of stomach or intestinal bleeding. This medication should be used during pregnancy only when clearly needed. This medication is not recommended during lactation.
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