Dienoestrol

Dienoestrol is a synthetic sex hormone. Dienoestrol is used to treat symptoms associated with menopause and for the suppression of lactation. Structurally similar to diethylstilibestestrol.


Brands
Adult Dose
Dose: 5 mg
Single Dose: 5 (5)
Frequency: As recommended.
Route: Intra Vaginal
Instructions: Maint. on alternate days, as required
Neonatal
Paedriatic
Characteristics
Dienoestrol also known as Dienestrol, Dienestrol, Dienestrol, Dienestrol. . It is of Synthetic origin and belongs to Alkyl Diphenol. It belongs to Oestrogen Agonist pharmacological group on the basis of mechanism of action and also classified in Sex Hormones pharmacological group.The Molecular Weight of Dienoestrol is 266.30.
Contraindications
Dienoestrol is contraindicated in conditions like Pregnancy,Endometrial hyperplasia,Hypersensitivity to the drug.
Effects
The severe or irreversible adverse effects of Dienoestrol, which give rise to further complications include Gall bladder disease.Dienoestrol produces potentially life-threatening effects which include Hypercalcemia, Breast cancer, Hepatic adenoma, Endometrial carcinoma, Thromboembolic disease, Hypercalcemia. which are responsible for the discontinuation of Dienoestrol therapy.The symptomatic adverse reactions produced by Dienoestrol are more or less tolerable and if they become severe, they can be treated symptomatically, these include Jaundice, GI upset, Weight gain, Elevated blood pressure, Hypersensitivity reactions, Hypersensitivity of lower vagina (vulva), Painful stimulation of breast, Endometrial bleeding, Changes in LFT, Salt retention, Water retention.
Indications
Dienoestrol is primarily indicated in conditions like Atrophic vaginitis, Senile vaginitis, Vulvar squamous hyperplasia, and can also be given in adjunctive therapy as an alternative drug of choice in Oestrogen deficiency.
Interactions
No data regarding the interactions of Dienoestrol was found.
Interfrence
Certain Endocrine and Liver Function Tests
Risks
Drug should not be given to Paediatrics, Pregnant Mothers, Geriatrics, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
Cream Store at room temperature.
Warnings
Avoid use during pregnancy or lactation and in childrens. It should not be used in case of damage to latex condoms and diaphragms.
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