Dicyclomine (HCl)

Dicyclomine (HCl) slows activity of the stomach and gastro-intestinal tract. Dicyclomine (HCl) used in treating spasm of gastro-intestinal tract and urinary tract and to reduce gastric acid in peptic ulceration. Dicyclomine (HCl) also used in diarrhea, irritable bowel syndrome, spastic colitis,m and biliary dyskinesia

Brands
BLISSCOLIC COLENTICON INFACOL
Adult Dose
Dose: 10 to 20 mg
Single Dose: 15 (15)
Frequency: 8 hourly
Route: PO
Instructions:
Neonatal
Dose: 0.5 mg/kg
Single Dose: 0.5 (0.5)
Frequency: 8 hourly
Route: oral
Instructions: Avoid in children less than 6 months of age
Paedriatic
Dose: 5 to 10 mg
Single Dose: 7.5 (7.5)
Frequency: As recommended.
Route: 3 to 4 times a day
Instructions:
Characteristics
Dicyclomine (HCl) also known as Dicycloverine Hydrochloride. . It is of Synthetic origin and belongs to Cyclohexyl Carboxylicacid. It belongs to Cholinergic muscarinic antagonist pharmacological group on the basis of mechanism of action and also classified in Gastrointestinal Anticholinergics/Antispasmodics and Antispasmodic Agent pharmacological group.The Molecular Weight of Dicyclomine (HCl) is 346.00.
Contraindications
Dicyclomine (HCl) is contraindicated in conditions like Glucoma,Reflux oesophagitis,Prostatic hypertrophy.
Effects
Dicyclomine (HCl) produces potentially life-threatening effects which include Respiratory arrest. which are responsible for the discontinuation of Dicyclomine (HCl) therapy.The symptomatic adverse reactions produced by Dicyclomine (HCl) are more or less tolerable and if they become severe, they can be treated symptomatically, these include Weakness, Dizziness, Drowsiness, Nausea, Tachycardia, Constipation, Blurred vision, Urinary retensionX, Problems of accomodation, Exacerbation of glaucoma, CNS effects, Photophobia, Xerostomia, dizziness.
Indications
Dicyclomine (HCl) is primarily indicated in conditions like Infantile colic, Irritable bowel syndrome, Symptomatic relief of GI-disorders, Urinary incontinence.
Interactions
No data regarding the interactions of Dicyclomine (HCl) was found.
Interfrence
Risks
Drug should not be given to Paediatrics, Pregnant Mothers, Geriatrics, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
Tab, Caps, Syrup Store Below 40°C. Protect from Sunlight and Moisture.
Warnings
Closely monitor patients for therapeutic response and side effects. Dicyclomine should not be used in high doses because may produce mental depression and mental distrubances. It should be used with caution in patients over 40 years, because may increase the risk of glaucoma. It should be used with caution in patients with asthma, heart or kidney diseases. It should be used with caution in infants and small children.
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