Dicobalt Edetate

Dicobalt Edetate is used as an antidote for cyanide poisoning.


Brands
Adult Dose
Dose: 8.571 mg/kg
Single Dose: 8.6 (8.571)
Frequency: As recommended.
Route: IV
Instructions: As Required
Neonatal
Paedriatic
Characteristics
. It is of Synthetic origin and belongs to Cobalt Chelate. It belongs to Chelating Agent pharmacological group.The Molecular Weight of Dicobalt Edetate is 406.10. It is weakly acidic drug.
Contraindications
Dicobalt Edetate is contraindicated in conditions like Hypersensitivity to the drug.
Effects
The severe or irreversible adverse effects of Dicobalt Edetate, which give rise to further complications include Vasodilation, Severe drop in BP, Angina.Dicobalt Edetate produces potentially life-threatening effects which include Anaphylactoid reactions, Convulsions, Collapse, Facial edema, Gross edema of pharynx, Neck edema. which are responsible for the discontinuation of Dicobalt Edetate therapy.The signs and symptoms that are produced after the acute overdosage of Dicobalt Edetate include Hypovolemia.The symptomatic adverse reactions produced by Dicobalt Edetate are more or less tolerable and if they become severe, they can be treated symptomatically, these include Headache, Nausea, Vomiting, Restlessness, Nervousness, Sweating, Facial flushing, Flushing, Coarse tremor of fingers.
Indications
Dicobalt Edetate is primarily indicated in conditions like Cyanide poisoning.
Interactions
No data regarding the interactions of Dicobalt Edetate was found.
Interfrence
Risks
If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
IV Inj Store Below 25°C. Protect from Sunlight.
Warnings
The adverse effect of Dicobalt Edetate is severe in the absence of cyanide, therefore it should not be administered unless cyanide poisoning is confirmed and poisoning is moderate or severe, i.e.,when conciousness is impaired.
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