DICLON PENFEN PENFEN AXFLAM AXFLAM AXFLAM MAGNOFENAC MAGNOFENAC MAGNOFENAC MAGNOFENAC GROFENAC GROFENAC GROFENAC ZULFENAC ZULFENAC SAFE-T ACCRED DICSODIM DICSODIM DICSODIM ARTONEC ARTONEC ULTRAFEN ULTRAFEN ULTRAFEN ULTRAFEN ARNIL ARNIL PHLOGIN PHLOGIN PHLOGIN CLOFNAC CLOFNAC ORTHOFENAC ORTHOFENAC ORTHOFENAC ORTHOFENAC ORTHOFENAC PROART Difam Plus DIFAM ARAM PLUS Aaram OCLONAC MOBIKARE DR MOBIKARE MOBIKARE MOBIKARE MOBIKARE MOBIKARE MOBIKARE OSTEOTEC OSTEOTEC VOLDOS VOLDOS DS-50 VOREN VOREN VOREN VOREN VOREN TYLOFENAC VOLTAGESIC VOLTAGESIC CO-FENAC CAMOTAREN CAMOTAREN VOLITE VOLITE WELDIC KARMEL FENACOLD FENACOLD FENACOLD FINFLEX SYNOFLAM DOFNAC ELIXOCAIN FLAREN FLAREN DICOFEN DICOFEN DICOFEN PHLOSAR OSTINAC ARTINIL VISODIC NAVIDIC MISO PLUS ARTINIL-K ARTICURE ARTINIL-K TOPICAL DIFLOSID DIFLOSID DIFLOSID DIFLOSID DIFLOSID CYTOPAN CYTOPAN PANSLAY PANSLAY XANY FICLORAN CLOREE MAXIT-L MAXIT-L SOFREN SOFREN MAXIT-S REMETHAN-R QUFEN REMETHAN REMETHAN INSTAREN INSTAREN ALTORON ALTORON ALTORON ALTORON EYE DROPS PROGILE PROGILE PROGILE DIMIS KESIFLAM DICLOFEN DYCLO-M DYCLO-M DYCLO-P DYCLO DYCLO DYCLO DYCLO DYCLO DYCLO DYCLO GR DYCLO GR DIACRON DIACRON DIACRON DANUM DANUM DENUM DENUM DENUM DENUM DURAFIN DICLOTEK CLORAN-S TECTOR PLUS MACDICOL MACDICOL MACDICOL ARSOFIN DEKER MATIC MATIC NOVOTRAN DICSOD DICSOD DICSOD DICLOKING LD JORWEL JORWEL JORWEL DICLOKING DICLOKING DICLOKING DICLOKING NOLTREN NOLTREN DICLOVAT DICLOVAT YARNIL ARTHOSURE DICLODENK KALDIC KALDIC DICLOBID DICLOBID DICLOBID SHARP DEFINA HEUMATIC NACLOF VOLTRAL VOLTRAL VOLTRAL VOLTRAL ANNUVA VOLTRAL EMULGEL VOLTRAL EMULGEL VOLTRAL EMULGEL OTAMIFENAC DICLODYN DICLODYN DOLACT EC OBLONEC OBLONEC DICSONEN RAPIGET RAPIGET RAPIGET NEUROFENAC NEUROFENAC NEUPROFENAC NEUPROFENAC DOLNOT DOLNOT DOLNOT ISMART ESMART ESMART ALCASAR PHLODIC PHLODIC DICOWISE LONAC LONAC LONAC LONAC LONAC ARTHROTEC-50 SONAL SONAL SONAL STOPAN DICLAC NECLOF NECLOF PULDOL PULDOL PULDOL MESOTEC DOLOFLAM DOLOFLAM DOLOFLAM DICLOPULSE DICLOPULSE DOLTRAN DOLTRAN OPHDIC RAKAFEN FASTAID FASTAID FASTAID FASTAID-R NOAK DIKLONAT-P DIKLONAT-P DIKLONAT-P ERWIN ERWIN DICLORAN DICLORAN DICLORAN DICLOTOL VOLFEN VOLFEN VOLFEN VOLFEN ROTEC ROTEC DEFNAC DEFNAC DEFNAC DEFNAC VURDON VURDON VURDON VURDON VURDON VURDON DINOFAC ARTHRON ARTHRON RHEUMATIN RHEUMATIN RHEUMATIN RHEUMATIN SMASH MOVEN SMASH 2 FENART ARTHO PLUS FIST FIST FIST FIST FIST FIST FIST FIST FIST ARTHO VOLNAC U-TRAN U-TRAN ZALIN ZALIN ZALIN DIROXIN FENAC FENAC FENAC FENAC SWISO SWISO SWISO MOTAAR MOTAAR MOTAAR MOTAAR MOTAAR DISTOL WONDRA WONDRA ZWITTER ZWITTER ZWITTER LOTTO LOTTO LOTTO D DICLOTAB DICLOTAB DICLOZAF DICLOZAF DICLOZAF DICLOZAF DICLOZAF DICLOZAF DICLOZAF DICLOZAF DICLOK VALRON VALRON DICLOGESIC DICLOGESIC DIAGESIC PLUS BIOFENAC BIOFENAC BIODIC SR DICLOMARK BIODIC BIODIC FLAMEX FLAMEX FLAMEX FLAMEX AMROFEC-L AMROFEC-L DICLOFENAC DICLOFENAC SODIUM AKSOFENAC AKSOFENAC DICORUM VALORON VALORON VOLMAX VOLMAX MECDAFIN DINOPEN DINOPEN DELFENAC DPAIN PLUS ARDI ARDI D-CAP DICLOFENAC SODIUM DURUM PHONAC DIFEN-STULLN UD DICLOSAK DICLOFENAC SODIUM VOLTADEX MB-DICLO MB-DICLO MB-DICLO REGOFENAC REGOFENAC REGOFENAC KONAC KONAC FENDIC S FENDIC S WOLFLAM-50 VOLTEC SPIC-FENIC SOFAC SOFAC SOFAC SOFAC SOFAC DICLOMIN ZEEDIC LOFSIM LOFSIM UFENAC UFENAC UFENAC UFENAC DICLOGIN DICLOGIN OCUFENAC ARDFENAC ARDFENAC MEDIFENAC TABLET RHEUDIC RHEUDIC VOLTEX SR VOLTEX DALTRAN OBERON FORTE OBERON FORTE DICLOFENA DICLOPRIME GEL HEGEN WOODTRAN SPON-K DAVITRAN DICAHIT DICTOL FORTE DICTOL FORTE DIC-50 DICLODIUM SHALTAREN DEPOGEN ORTHONIL ORTHONIL-P ATCORA DICLOWAN DICLOWAN DICLOSCOT-XR PAINREST PAINREST PAINREST PAINREST ELIXON ODIC LISODIM LISODIM LISODIM MEDIFLAM DICLOCIN DICLOCIN ARTHONIL ARTHONIL DIXIE SAMOTEC-50 CYCLOFENAC CYCLOFENAC VODIM VODIM OPHTH-DICLOFEN EUROFENAC MISOFEN FEN-S PAIN-AID PLUS PAIN-AID PLUS DICLOSCOST-XR DICLOSCOT DICLOSCOT DICLOSCOT DICLOSCOT DICLOSCOT HI-NIL SR DIC-S VELFENAC FORGENAC DICIUM OLISOD SR GLEN SIDILIVE SR SR INFLAMAC INFLAMAC VOLTREE DIC LINZAC LINZAC A-FENAC PLUS MOTIFIVE RUMSO DEFLOQUIN DICLOASIA ANIFEN CLOFENAC CLOFENAC VOVERON NOADIC NOADIC MEGAFENAC DICLOWAL DICLOWAL LASERON DIFSOM DILON SR DILON ANAREN ANAREN ANAREN ANAREN ANAREN DICLORAS DICLORAS AEROTEC ANAC ANAC ARTIFEN TOPICAL ARTIFEN ARTIFEN ARTIFEN TEKNOFENAC ZICLOFEN-P ZICLOFEN-S ZICLOFEN ZICLOFEN ZICLOFEN-DR SONIFAC DICLOREX OLIFEN DICLOYAN-S DICLOYAN-S DICLOYAN-S RHEUYAN RHEUYAN DICLOFAZ DICLOFAZ GLIF-S JFENAC DICLOFAST G-RON GL-RON DANOTECH CYCLOFEN LOPRAN-SR LOPRAN-S ALFAFENAC ALFAFENAC ALFAFENAC ALEVE FENODIC DFENAC DFENAC VOLFENAC VOLFENAC VOLFENAC PAINSTOP FENAL T FENAL FENAL RHEUMAGEL RHEUMAGEL-50 INFLEX DIANIC DIANIC DIANIC DEJAFEN-S DEJAFIN WENDIM ARTISAF FRENDIK-S FIEDIC OSTEONAC OSTEONAC DICLOGRAY PLUS DICLOGRAY DICLOGRAY PAINNIL PAINNIL NADIUM HECLOFEN HECLOFEN MAKAID MAKAID MAKAID DEMSUN ARAAM ARAAM SR DICNY OTTOFENAC OTTOFENAC OTTOFENAC DICLOAP DICLOAP DICLOMAC DICLOMAC DICLOMAC MEDIFENAC INJECTION POFAC Misodoc DICLOX DICLOX DICLOX JICLOFEN-S XINIA XINIA PRODIUM PRODIUM DICWAY-C DICWAY-C DICLOZAN SR HELTRON HONDIC HONDIC DEWIS DEWIS NATAN EPHANAC SR EPHANAC EPHANAC EPHANAC EPHANAC LIFDIC SANG-SR SANG-SR DICLONIC DR LOTOFENAC SR SR LOTOFENAC LOTOFENAC LOTOFENAC LODIC LODIC LODIC DC-NA DC-NA PRONIC MOTIV MOTIV AMFAC DICLOADVAN DICLOADVAN DICLOADVAN DICLORADVAN FENUM SR DIFNAC PAIN-X DIFNAC-E ARTHROTOP MED-DICLO MEDONAC MEDONAC Natwel Natwel DYCNOM DYCNOM DYCLOXAN-SR DEBORN-L DEBORN DEBORN TRICLO-K TRICLO-K TRICLO TRICLO TRICLO FLAMOWAN DICLOWAN SR DICLOWAN SR MARINAC-S MARINAC VOLDEN FORT VOLDEN FORT PHLONAC SR DYOSAL SR SALDIC VOTTSUN VECTRA SR VECTRA FASDIC DICLOSAF DICLOSAF D-SODIUM AGONIL VOLTAB VECLOFEN VECLOFEN VECLOFEN SR FARCLODIUM SR AFNAC VOREN-SR FENADIUM DISSIUM RODIC RODIC RODIC RODIC SR SR EVERSHAFA NOZIN NOZIN BRAVO FENDOL FENDOL LIGNORAN FLEXY FLEXY FLEXY FLEXY DICLOSAVE DICLOSAVE DICLOSAVE DPROSTOL OCUNAF HECLORON-L VOLTREX ARAMFEN ARAMFEN SATAFENAC DICLOFENAC DISOF MYRDICLAIN NATRIUM WELFENAC PAIN TREAT TREAFEN ECLOPROST RAXONAC RAXONAC Simfenic

Dose: 75 to 0 mg
Single Dose: 38 (37.5)
Frequency: 12 hourly
Route: Deep IM
Instructions: For maximum 2 days Continue with tabs if necessary. If needed frequency may increased to twice/day.

Dose: Not used in this age group
Single Dose:
Frequency:
Route:
Instructions:

Dose: 0.25 to 0.75 mg/kg
Single Dose: 0.5 (0.5)
Frequency: 6 hourly
Route: Oral
Instructions: -

. It is of Synthetic origin and belongs to Amino Phenyl Acetate. It belongs to Cyclo-oxygenase inhibitor pharmacological group on the basis of mechanism of action and also classified in Analgesics and Anti-inflammatory Agents pharmacological group.The Molecular Weight of Diclofenac (Na) is 318.10. It is weakly alkaline drug and Its pKa is 4.

Diclofenac (Na) is contraindicated in conditions like Asthma,Peptic ulcer,Hypersensitivity,GI bleeding,Renal impairment,Hemorrhagic diathesis.

The severe or irreversible adverse effects of Diclofenac (Na), which give rise to further complications include Anaphylactoid reactions, Nephrotic syndrome, Blood dyscrasias, Peptic ulceration, Bleeding, Lower gut disorders, Papillary necrosis.Diclofenac (Na) produces potentially life-threatening effects which include Blood dyscrasias, perforation of peptic ulcer, Anaphylaxis, GI hemorrhage. which are responsible for the discontinuation of Diclofenac (Na) therapy.The signs and symptoms that are produced after the acute overdosage of Diclofenac (Na) include Nausea, Vomiting, Melena, Jaundice, Unconsciousness, Dizziness, Headache, Hepatopathy, Oliguria or anuria, Myoclonic encephalopathy, GI hemorrhage, Somnolence, Upper abdominal pain, Hiccup.The symptomatic adverse reactions produced by Diclofenac (Na) are more or less tolerable and if they become severe, they can be treated symptomatically, these include Flatulence, Dizziness, Vertigo, Tiredness, Headache, Drowsiness, Irritability, Nausea, Vomiting, Anorexia, Diarrhea, Anxiety, Tremors, Abdominal cramps, Constipation, Insomnia, Rashes, Pain, Itching, Burning, Dyspepsia, Depression, Nightmares, Epigastric pain, Taste disturbances, Eye irritation, Paresthesias, Vision disturbances, Hearing disturbances, ulceration of conjuctiva and cornea,.

'Diclofenac (Na) is primarily indicated in conditions like Acute exacerbation of pain and post operative pain, Acute gout, Ankylosing spondylitis, Bursitis, Gastro-oesophageal reflux disease, Juvenile chronic arthritis, Low back pain, Musculoskeletal disorders, Osteoarthritis, Peptic ulcer, Periarthritis, Pernicious anaemia and other macrocytic anaemias, Post-operative pain, Prevention of postoperative pain, Rheumatoid arthritis, Sprains, Strains, Tendinitis, Tenosynovitis, Tobacco amblyopia and leber''s optic atrophy, Ureteric colic.'

Diclofenac (Na) is known to interact with other drugs, the details of drug interactions is as follows:DrugDetailsSeverityOnsetManagementCarbacholChlorocarbacholCholestyraminecholestyramine reduce bioavailability of diclofenacCyclosporin Anephrotoxity may occurDigoxinDiclofenac increases the plasma concentration of digoxin.Lithiumdecrease in plasma concentration of diclofenac by sucralfateMethotrexateDiclofenac increases the plasma concentration of methotrexate by interfering with renal elimination results in increased toxicity and pharmacological effects.MajorClosely monitor for signs of bone marrow suppression and nephrotoxicity. Avoid any other over-the-counter NSAID product.NateglinideConcurrent use may potentiate the hypoglycemic action of Nateglinide.NitrendipineMay increase the levels/effects of nitrendipine.Salicylic AcidSucralfateTriamterenetraimterene deteriorate the renal function of diclofenacTriamtereneConcomitant use of these agents inhibit the renal synthesis of prostaglandin which help to maintain glomerular filtration and thus adversely affect the renal function result in hyperkalemia and elevation in blood pressure.ModerateClosely monitor renal function and blood pressure of patient. Avoid dehydration. Drugs should be discontinued ifhyperkalemia or renal insufficiency develop.Warfarin (Na)Diclofenac may enhance the anticoagulant effect of Warfarin. ModerateDelayedPatients receiving Warfarin should be instructed to not initiate Diclofenac without consulting his/her healthcare professional (nonacetylated salicylates might be safer alternatives). Acetaminophen is usually a good antipyretic and analgesic choice for patients taking Warfarin. Monitor for increased signs and symptoms of bleeding if Warfarin and Diclofenac are used concomitantly. These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

Drug should not be given to Pregnant Mothers, Cardiac / Hypertensive Patients, and patients suffering from Kidney dysfunction.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.

Tab Store Below 40°C. Protect from Sunlight and Moisture.

Diclofenac sodium should be used with caution in patients with intrinsic coagulation defects and those on anticoagulant therapy. It should be used with caution in patients with compromised cardiac function, hypertension and other conditions predisposing to fluid retention. It should be used with extra care in the presence of existing uncontrolled infection. Perform periodic auditory (hearing) function test during chronic therapy. Discontinue drug if skin reaction occurs.