VORICONAZOLE

Voriconazole is a triazole antifungal agent. Voriconazole is designated chemically as (2R,3S)-2-(2,4-difluorophenyl)-3-(5-fluoro-4­ pyrimidinyl)-1-(1H-1,2,4-triazol-1-yl)-2-butanol. It is available as a lyophilized powder for solution for intravenous infusion, film-coated tablets for oral administration, and as a powder for oral suspension.

Brands
VORIF VORIF
Adult Dose
Neonatal
Paedriatic
Characteristics
. It is of Synthetic origin and belongs to phenylpropylamines. It belongs to Antifungals pharmacological group.The Molecular Weight of VORICONAZOLE is 349.31.
Contraindications
VORICONAZOLE
Effects
The symptomatic adverse reactions produced by VORICONAZOLE are more or less tolerable and if they become severe, they can be treated symptomatically, these include Headache, Nausea, Vomiting, Fever, Tachycardia, Chills, Hallucination, Visual disturbances, Rash, Tachycardia.
Indications
VORICONAZOLE is primarily indicated in conditions like Candidiasis.
Interactions
No data regarding the interactions of VORICONAZOLE was found.
Interfrence
Liver Function Test (LFT)
Risks
Drug should not be given to Paediatrics, Pregnant Mothers, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
Injection Store Between 15°C-30°C. Tablet Powder for Oral Suspension Store Below 15°C.
Warnings
Hepatic Toxicity: Serious hepatic reactions reported. Evaluate liver function tests at start of and during voriconazole therapy. Visual Disturbances (including optic neuritis and papilledema): Monitor visual function if treatment continues beyond 28 days. Embryo-Fetal Toxicity: Do not administer to pregnant women unless the benefit to the mother outweighs the risk to the fetus. Inform pregnant patient of hazard. Patients with Hereditary Galactose Intolerance Lapp Lactase Deficiency or Glucose-Galactose Malabsorption: Do not use. Arrhythmias and QT Prolongation: Correct potassium, magnesium and calcium prior to use; caution patients with proarrhythmic conditions. Infusion Related Reactions (including anaphylaxis): Stop the infusion. Dermatological Reactions: Discontinue for exfoliative cutaneous reactions or phototoxicity. Avoid sunlight due to risk of photosensitivity.Skeletal Events: Fluorosis and periostitis with long-term voriconazole therapy. Discontinue if these events occur
Back to List

Any information that appears on this website page is provided for the purpose of general information. This website has been compiled in good faith by HMIS.Online. However, no guarantee is made as to the completeness, validity or accuracy of the information it contains.