Canagliflozin

Canagliflozin is an inhibitor of sodium glucose co-transporter 2 (SGLT2), the transporter responsible for reabsorbing the majority of glucose filtered by the kidney.It is chemically known as (1S)-1,5-anhydro-1-[3-[[5- (4-fluorophenyl) 2 thienyl]methyl]-4-methylphenyl]-D glucitol hemihydrate. Canagliflozin is used as an adjunct to diet and exercise to improve glycemic control in adult with Type 2 Diabetics Mellitus

Brands
Adult Dose
Neonatal
Paedriatic
Characteristics
. It is of Synthetic origin and belongs to C- Glycosyl. . The Molecular Weight of Canagliflozin is 453.53.
Contraindications
Canagliflozin
Effects
The symptomatic adverse reactions produced by Canagliflozin are more or less tolerable and if they become severe, they can be treated symptomatically, these include urinary tract infection, female genital mycotic infections, increased urination.
Indications
Canagliflozin is primarily indicated in conditions like Type II diabetes mellitus.
Interactions
No data regarding the interactions of Canagliflozin was found.
Interfrence
Risks
Drug should not be given to Paediatrics, Pregnant Mothers, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
Film Coated Tablet Store Below 30°C.
Warnings
Hypotension,impairment in Renal Function, Hyperkalemia, Hypoglycemia, Hypersenitivity reaction, increased LDL-C, all these condition required caution when treated with canagliflozin.
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