Dimethyl Fumarate

dimethyl fumarate which is also known by its chemical name, dimethyl (E) butenedioate, (C6H8O4). It is indicated for the treatment of patients with relapsing forms of multiple sclerosis

Brands

Adult Dose

Neonatal

Paedriatic

Characteristics

. It is of Synthetic origin. . The Molecular Weight of Dimethyl Fumarate is 114.13.

Contraindications

Dimethyl Fumarate

Effects

The symptomatic adverse reactions produced by Dimethyl Fumarate are more or less tolerable and if they become severe, they can be treated symptomatically, these include Nausea, Diarrhea, Abdominal pain, Flushing.

Indications

Dimethyl Fumarate is primarily indicated in conditions like Multiple sclerosis.

Interactions

No data regarding the interactions of Dimethyl Fumarate was found.

Interfrence

Risks

Drug should not be given to Paediatrics, and Pregnant Mothers.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.

Storage

Delayed release Capsule Store Between 20°C-25°C. Protect from Sunlight.

Warnings

Dimethyl fumarate may cause lymphopenia. A recent CBC should be available before initiating treatment.A CBC is recommended annually, and as clinically indicated. Consider withholding treatment in patients with serious infections.Tecfidera has not been studied in patients with severe renal or severe hepatic impairment and caution should, therefore, be used in these patients. Tecfidera has not been studied in patients with severe active gastrointestinal disease and caution should, therefore, be used in these patients. Flushing

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