Tilmanocept

Tilmanocept is a new chemical entity and a novel radiodiagnostic imaging agent, targeting the radioisotope, technetium-99m to a mannose-binding protein that resides on the surface of dendritic cells and macrophages.it is used for lymphatic mapping with a hand- held gamma counter to assist in the localization of lymph nodes draining a primary tumor site in patients with breast cancer or melanoma. The chemical name of tilmanocept is dextran, 3 [(2-aminoethyl)thio]propyl 17-carboxy-10, 13, 16-tris(carboxymethyl)-8-oxo-4-thia-7, 10, 13, 16-tetraazaheptadec-1-yl 3-[[2-[[1-imino-2-(D mannopyranosylthio)ethyl]amino]thio]propyl ether

Brands
Adult Dose
Neonatal
Paedriatic
Characteristics
. It is of Synthetic origin. It belongs to Radiopaque Agents pharmacological group on the basis of mechanism of action. The Molecular Weight of Tilmanocept is 15.00.
Contraindications
Tilmanocept
Effects
The symptomatic adverse reactions produced by Tilmanocept are more or less tolerable and if they become severe, they can be treated symptomatically, these include injection site pain, injection site irritation.
Indications
Tilmanocept is primarily indicated in conditions like Breast cancer, Squamous cell carcinoma.
Interactions
No data regarding the interactions of Tilmanocept was found.
Interfrence
Risks
Drug should not be given to Paediatrics, Pregnant Mothers, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
injection Store at room temperature, Between 20°C-25°C.
Warnings
Hypersensitivity: Ask patients about prior reactions to drugs, especially dextran or modified forms of dextran. Observe for hypersensitivity signs and symptoms Radiation Risks:Any radiation-emitting product may increase the risk for cancer, especially in pediatric patients. Adhere to the dose recommendations and ensure safe handling to minimize the risk for excessive radiation exposure to either patients or health care workers.
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