Ospemifene

OSPHENA is an estrogen agonist/antagonist.The chemical designation is Z-2-[4-(4-chloro-1,2-diphenylbut-1-enyl)phenoxy]ethano. It is used in the treatment of moderate to severe dyspareunia, a symptom of vulvar and vaginal atrophy, due to menopause.

Brands

Adult Dose

Neonatal

Paedriatic

Characteristics

. It is of Synthetic origin. . The Molecular Weight of Ospemifene is 378.50.

Contraindications

Ospemifene

Effects

The symptomatic adverse reactions produced by Ospemifene are more or less tolerable and if they become severe, they can be treated symptomatically, these include Vaginal discharge, Hot flushes, Hyperhidrosis, muscle spasm, genital discharge.

Indications

Interactions

No data regarding the interactions of Ospemifene was found.

Interfrence

Risks

Drug should not be given to Paediatrics, Pregnant Mothers, Cardiac / Hypertensive Patients, patients suffering from Liver Malfunction, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.

Storage

Warnings

Venous Thromboembolism: Risk of DVT and pulmonary embolism, Known, suspected, or history of breast cancer, Severe Hepatic Impairment, cardiovascular disorder like stroke, coronary heart disease, endometrial cancer, caution mst be taken in these disease.

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