Alogliptin

alogliptin is a selective, orally bioavailable inhibitor of the enzymatic activity of dipeptidyl peptidase-4 (DPP-4). Chemically, alogliptin is prepared as a benzoate salt, which is identified as 2-({6-[(3R)-3­aminopiperidin-1-yl]-3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)­yl}methyl) benzonitrile monobenzoate.Alogliptin is indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus

Brands
Adult Dose
Neonatal
Paedriatic
Characteristics
. It is of Synthetic origin and belongs to benzonitrile monobenzoate. It belongs to DPP-4 inhibitor pharmacological group on the basis of mechanism of action. The Molecular Weight of Alogliptin is 461.51.
Contraindications
Alogliptin
Effects
The symptomatic adverse reactions produced by Alogliptin are more or less tolerable and if they become severe, they can be treated symptomatically, these include Headache, Nasopharyngitis, Upper respiratory tract infections.
Indications
Alogliptin is primarily indicated in conditions like Type II diabetes mellitus.
Interactions
No data regarding the interactions of Alogliptin was found.
Interfrence
Risks
Drug should not be given to Paediatrics, patients suffering from Liver Malfunction, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
Tablet Store at room temperature, Between 20°C-25°C.
Warnings
Acute pancreatitis, Hypersensitivity, hepatic effects, hypoglycemia, macrovascular outcomes.
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