Sevelamer HCl

'Sevelamer HCl is non absorbed phosphate binder, indicated for the control of serum phosphorus( hyperphosphataemia) in patients with chronic kidney disease on dialysis. chemically, it is known as poly(allylamine-co-N,N''-diallyl-1,3-diamino-2-hydroxypropane) hydrochloride.'

Brands
RENAVEL SALVER
Adult Dose
Neonatal
Paedriatic
Characteristics
. It is of Synthetic origin and belongs to Polymeric Amine. . The Molecular Weight of Sevelamer HCl is 186.08.
Contraindications
Sevelamer HCl
Effects
The symptomatic adverse reactions produced by Sevelamer HCl are more or less tolerable and if they become severe, they can be treated symptomatically, these include Flatulence, Nausea, Vomiting, Diarrhea, Constipation, Abdominal pain, Dyspepsia, dyspepsia, G.I adverse reactions.
Indications
Sevelamer HCl is primarily indicated in conditions like Hyperphosphataemia in renal failure.
Interactions
No data regarding the interactions of Sevelamer HCl was found.
Interfrence
Risks
Drug should not be given to Paediatrics, Pregnant Mothers, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
Tablet Store Between 15°C-30°C. Refrigeration and Freezing is not recommended. Protect from Moisture.
Warnings
The safety and efficacy of sevelamer HCl in patients with dysphagia, swallowing disorders, severe GI motility disorders including severe constipation, or major GI tract surgery have not been established. Caution should be exercised when used in patients with these GI disorders. Monitor for Reduced Vitamins D, E, K (clotting factors) and Folic Acid Levels. Bicarbonate and chloride levels should be monitored.
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