Dose: 0.071 to 0.143 mg/kg
Single Dose: 0.11 (0.107)
Frequency: 4 hourly
Route: IM
Instructions: -

Dose: 0.05 to 0.1 mg/kg
Single Dose: 0.075 (0.075)
Frequency: 4 hourly
Route: Intra Muscular
Instructions: -

Dose: 0.05 to 0.1 mg/kg
Single Dose: 0.075 (0.075)
Frequency: 4 hourly
Route: Intra Muscular
Instructions: -

Diamorphine (HCl) also known as Diacetylmorphine HCl. . It is of Semi Synthetic origin and belongs to Opioid. It belongs to OPIATE agonist pharmacological group on the basis of mechanism of action and also classified in Analgesics and Anti-inflammatory Agents and Analgesic-Narcotic pharmacological group.The Molecular Weight of Diamorphine (HCl) is 423.90. Its pKa is 7.6.

Diamorphine (HCl) is contraindicated in conditions like Respiratory disease,Biliary colic,Raised intracranial pressure,Head injury.

The severe or irreversible adverse effects of Diamorphine (HCl), which give rise to further complications include Nephrotic syndrome, Pulmonary edema, Thrombocytopenic purpura, Renal amyloidosis, Rhabdomyolysis, Reduced GFR (glomerular filtration rate), Decrease in sexual desire.The signs and symptoms that are produced after the acute overdosage of Diamorphine (HCl) include Nausea, Vomiting, Pulmonary edema, ECG alterations, Confusion, Respiratory depression, Hypothermia, Miosis, Dysphoria, Sedation, Respiratory failure, Sinus tachycardia, Rhabdomyolysis.The symptomatic adverse reactions produced by Diamorphine (HCl) are more or less tolerable and if they become severe, they can be treated symptomatically, these include Nausea, Vomiting, Constipation, Dry mouth, Pruritus, Sedation, SweatingX, Miosis, Respiratory depression, Euphoria, Mental clouding, Calmness, Hypothermia, Spasm of the sphinctor of oddi, Hypertension, Dependence, Dry mouth.

Diamorphine (HCl) is primarily indicated in conditions like Chronic pain, Cough, Opioid agonist dependence, Severe acute pain.

No data regarding the interactions of Diamorphine (HCl) was found.

Interfere with the quantification of morphine by radioimmunoassay.

Drug should not be given to Pregnant Mothers, patients suffering from Kidney dysfunction, patients suffering from Liver Malfunction, Geriatrics, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.

Inj Store Below 30°C. Protect from Sunlight.

The long term administration of diamorphine will result in physical dependence and therefore an obstinence syndrome will occur if diamorphine therapy is abruptly discontinued. Therefore gradually reduces the dosage regimen to prevent the obstinence syndrome. The dose and dosing interval of diamorphine must be titrated against the individual patient reports of their pain.