Desvenlafaxine

Desvenlafaxine, also known as O-desmethylvenlafaxine, is an antidepressant of the serotonin-norepinephrine reuptake inhibitor .Desvenlafaxine is a synthetic form of the major active metabolite of venlafaxine.

Brands
LAFAXINE LAFAXINE
Adult Dose
Neonatal
Paedriatic
Characteristics
Desvenlafaxine also known as O-desmethylvenlafaxine, O-desmethylvenlafaxine, O-desmethylvenlafaxine. . It is of Synthetic origin. It belongs to Antidepressant pharmacological group.The Molecular Weight of Desvenlafaxine is 263.38.
Contraindications
Desvenlafaxine
Effects
The symptomatic adverse reactions produced by Desvenlafaxine are more or less tolerable and if they become severe, they can be treated symptomatically, these include Dizziness, Nausea, Anxiety, Constipation, Insomnia, Somnolence, Decreased appetite, Hyperhidrosis, dizziness, male sexual function disorders, decreased appetite.
Indications
Desvenlafaxine is primarily indicated in conditions like Major Depressive Disorder.
Interactions
Desvenlafaxine is known to interact with other drugs, the details of drug interactions is as follows:DrugDetailsSeverityOnsetManagementAspirinNSAID or aspirin may potentiate the risk of bleedingcareful mointoring is required at the initiation and discontinution of therapyVortioxetineincreases the level of vortioxetinemonitor closely, use alternativeWarfarin (Na)Altered anticoagulant effects, including increased bleeding Patients receiving warfarin therapy should be carefully monitored when PRISTIQ is initiated or discontinuedcarefully monitored when PRISTIQ is initiated or discontinued These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Interfrence
change in Cholestrol levelchange in lipoprotein levelchange in triglycerides
Risks
Drug should not be given to Paediatrics, Pregnant Mothers, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
Tablet Store Between 20°C-25°C. Refrigeration and Freezing is not recommended. Protect from Sunlight.
Warnings
Suicidal Thoughts and Behaviors in Adolescents and Young Adults, Serotonin Syndrome, Elevated Blood Pressure, Narrow-Angle Glaucoma, Abnormal Bleeding, Activation of Mania/Hypomania, Discontinuation Syndrome, seizure, Hyponatremia and Interstitial lung disease an eosinophilic Pneumonia
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