Lactitol Monohydrate

Lactitol is synthetic disaccharide osmotic laxatives and analogue of lactulose. With its more pleasant taste, lactitol is better tolerated and morepalatable. Lactitol monohydrate is used as an oral powder or solution in the management of hepatic encephalopathy and in constipation.

Brands
LACASIL
Adult Dose
Neonatal
Paedriatic
Characteristics
. It is of Synthetic origin and belongs to Lactulose(disacchride analogue). It belongs to Laxatives pharmacological group on the basis of mechanism of action. The Molecular Weight of Lactitol Monohydrate is 362.30.
Contraindications
Lactitol Monohydrate
Effects
The symptomatic adverse reactions produced by Lactitol Monohydrate are more or less tolerable and if they become severe, they can be treated symptomatically, these include Abdominal distension, Flatulence, Nausea, Vomiting, Dyspepsia, Cramps, Epigastric pain, Abdominal discomfort, Anal pruritus, dyspepsia.
Indications
Lactitol Monohydrate is primarily indicated in conditions like Constipation, Hepatic encephalopathy.
Interactions
No data regarding the interactions of Lactitol Monohydrate was found.
Interfrence
Risks
If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
syrup Store . Refrigeration and Freezing is not recommended. Protect from Sunlight, Moisture and Heat. Sachet Store . Refrigeration and Freezing is not recommended. Protect from Sunlight, Moisture and Heat.
Warnings
Absorption of lactate from colonic metabolism of lactitol can potentyially result in acid- base disturbances, and diarrhoea induced by lactitol can be associated with hypokalemia and hypernatremia. potassium deficiency may increae the risk of toxic effects of glycoisde in patients receiving concomitnt therapy. periodic monitoring of serum electrolytes, blood glucose and blood lactate is suggested.if watery stools are noticed, one should either reduce the quantity of administration or suspend administration.Blood electrolyte levels should be monitored regularly in elderly or debilitated patients on long term treatment. Patient who complain of nausea should be advised to take with meal. lactitol is not recommeded in case of ileostomy or colostomy. Fecal impaction should be treated by alternative methods prior to using lactitol.
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