COMBINOL-D COMBINOL DM COUGH ALCOF D KOMKOLD-DM KOMKOLD-DM SYREX RHINOTUSSAL RHINOTUSSAL EPINOL-DM EPINOL-DM DOSACOREX-D DOSAFED-DM ZTROMED PABALGESIC BRINTYL BRINTYL OROLIN-DM FEROCOL-D PULMOFED PULMOFED PULMOFED COCIL MEDI-FLU DEXTROMETHORPHAN DEXTROMETHORPHAN HISTAMOL-D HISTAMOL-D ACTIFED-DM ACTIFED-DM ACTIFED-DM DELSYM ZODEC ZODEC CUFGO DM NIGHTCARE NIGHTCARE JUMSOL BRONCORIDE-DM TUSCOLIN-D KARMOL-NEO ASKOREX INVOFLOX-D METRAFED METRAFED DEXODINE DEXODINE GLYCODIN GLYCODIN GLYCODIN UNIREX-D UNIREX-D BRONCODYL-D BRONCODYL-D DEXTROMETHORPHAN TRIAMINIC-DM TRIAMINIC COUGH (CHILD) TRIAMINIC FLUE,COUGH NAFRALINE-DM COSOME RELTUS-DM TUSSIVIL BENYLIN-DM BENATUSS COREX-D COREX-D BENYLIN-E TRICOS TRICOS PACIFICS-DM PACIFICS-DM PACIFICS J&J PACIFICS J&J NOVATUS PACIFICS-DM DECONGESTANT PACIFICS-DM DECONGESTANT BUCKLEYS JACK & JILL BUCKLEYS JACK & JILL BENICAL TYNO COUGH TYNO COUGH TYNO-SF COUGH ROFLIN DM TEXCOL-DMD TEXCOL-DM TEXCOL-DM TEXCOL PLUS HYDRYLLIN ANTI FLU HYDRYLLIN-DM HYDRYLLIN-DM SPENSID TORAX-G TORAX-DM PULMAX PULMAX UNEXOFED DM BROXOL-DM PECTUS PENTALLIN D.M BACTOCEF COLDREX COLDREX ADICOS-M ADICOS-M RESPIRATE-DM BABYNOL COUGHSOL CONIL CONIL CONIL BROVENOL DM BROVENOL DM TUSSEX BAGODRYL DM LISKOFID DM REGOFID-DM REGOFID-DM REGOFID-DM BRONCHOSAFE DM KOFNIL-D KOFNIL-D KUFZEE DEXAPHAN COFSED COFSED COFCOLD DM BRONCOS DM IMCOTUS COUGH-FLU COUGH-FLU DAGNUM COUGH COFCINA-D COFCINA-D MULTI-ACTION MULTI-ACTION AVALON AVALON MUCLEAR DM XR MUCLEAR DM XR AVALON FLU BIOLLIN DM XATUS D XATUS D PLASIL J&J PLASIL J&J BRODEX TRACODIL DM RONDEC C COFCOL COFCOL COFCOL RONDEC RONDEC DENOL-DM BRONCODYL BRONCODYL CHILMINIC PULMOX DM COUGHMED DM COUGHMED DM COUGH-DM BELINKTUS DM DEXTROPHAN WYDRYLIN DM

Dose: 10 to 30 mg
Single Dose: 20 (20)
Frequency: 8 hourly
Route: PO
Instructions: Frequency may be increased upto 4 times/day if needed.

Dose: 0.312 mg/kg
Single Dose: 0.31 (0.312)
Frequency: 8 hourly
Route: Oral
Instructions:

Dose: 5 to 10 mg
Single Dose: 7.5 (7.5)
Frequency: 4 hourly
Route: To a maximum of 60 mg in 24 hours.
Instructions:

Dextromethorphan also known as Methorphinan. Dextromethorphan (HBr), Dextromethorphan (HBr) are the derivatives of Dextromethorphan. It is of Synthetic origin and belongs to Morphine. It belongs to Anti-tussives pharmacological group on the basis of mechanism of action and also classified in Antituberculous Drugs pharmacological group.The Molecular Weight of Dextromethorphan is 370.30. Its pKa is 8.3.

Dextromethorphan is contraindicated in conditions like Asthma,Respiratory failure,Liver diseases,Emphysema.

The severe or irreversible adverse effects of Dextromethorphan, which give rise to further complications include Dependency.The signs and symptoms that are produced after the acute overdosage of Dextromethorphan include Excitation.The symptomatic adverse reactions produced by Dextromethorphan are more or less tolerable and if they become severe, they can be treated symptomatically, these include Dizziness, Drowsiness, Vomiting, Restlessness, Mental confusion, Excitation.

Dextromethorphan is primarily indicated in conditions like Dry cough.

Dextromethorphan is known to interact with other drugs, the details of drug interactions is as follows:DrugDetailsSeverityOnsetManagementAbiraterone acetateDextromethorphan is a substrate of CYP2D6. Abiraterone increases the systemic exposure of dextromethorphan by approximately 2.9 fold. The AUC for dextrorphan, the active metabolite of dextromethorphan, increases approximately 33%.Amiodarone (HCl)Fluoxetine (HCl)Haloperidoliloperidoneincrease in total exposure and an increase in the maximum plasma concentrations of Dextromethorphandose of iloperidone should be reducedMitomycin CMoclobemideParoxetinePhenelzinePropafenone (HCl)QuinidineSibutramineSodium AcetateAlkalization of the urine decreases the urinary excretion increases the elimination half-life of Dextromethorphan.ModeratePatients should be monitored for toxic effects such as tremor, anxiety, insomnia, irritability, or nervousness. Dosage reductions may be required.Thioridazine (HCl)TocilizumabToclizumab decreases exposure of Dextromethorphan These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

Intereference with diagnostic test result for skin test

Drug should not be given to Paediatrics, Pregnant Mothers, patients suffering from Liver Malfunction, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.

Caps, Lozenzes Store in a well closed container, at room temperature. Syrup, Susp Store at room temperature. Do not Freeze. Protect from Sunlight.

Dextromethorphan should be used with caution in patients with any pre-existing kidney disease, heart disease, lungs disease, asthma, emphysema, high blood pressure, hyperthyroidism, diabetes, glaucoma, prostate trouble or if have any allergy. This medication should be used only if clearly needed during pregnancy or lactation.