TEARS NATURAL II OPTITEARS PLASMAX -70 TEARS FORTE ONKOVERTIN IN NACL 0.9% SAVIOSOL CHAYRAL SERENE AQUATEARS AQONA TEAS EYE DROPS MACSOLATE D MACSOLATE D

Dose: 20 to 40 ml/min
Single Dose: 30 (30)
Frequency: As recommended.
Route: IV Inf
Instructions: Initially for 12.5 to 50 Minutes

Dose: 10 ml/kg
Single Dose: 10 (10)
Frequency: 24 hourly
Route: IV Infusion
Instructions: Maintenance for 5 Days

. It is of Semi Synthetic origin and belongs to Polysaccharide. It belongs to Plasma Protein Fractions and Plasma Volume Expander pharmacological group.The Molecular Weight of Dextran is 42500.00.

Dextran is contraindicated in conditions like Congestive heart failure,Haemostatic defect,Renal disease with oliguria or anuria.

The severe or irreversible adverse effects of Dextran, which give rise to further complications include Renal damage, Acute renal failure, Volume overload, Bleeding.Dextran produces potentially life-threatening effects which include Anaphylactoid reactions. which are responsible for the discontinuation of Dextran therapy.The symptomatic adverse reactions produced by Dextran are more or less tolerable and if they become severe, they can be treated symptomatically, these include Nausea, Vomiting, Abdominal pain, Urticaria, Allergic reactions, Nasal congestion, Wheezing, Oliguria.

Dextran is primarily indicated in conditions like Anaphylactic reactions, Conditions associated with peripheral local slowing of the blood flow, Deep vein thrombosis prophylaxis, Hypovolaemia, Pulmonary embolism prophylaxis, Short-term blood volume expansion, Thromboembolism, Vascular flow improvement, and can also be given in adjunctive therapy as an alternative drug of choice in Toxaemia of pregnancy.

Dextran is known to interact with other drugs, the details of drug interactions is as follows:DrugDetailsSeverityOnsetManagementCertoparinChlortetracycline (HCl)ClodronateHeparin (Na) and Heparin (Cl)Promethazine (HCl)Tinzaparin SodiumConcurrent use may increase the risk of bleeding.If coadministration is essential, close clinical and laboratory monitoring of these patients is advised. These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

Interfere with Blood Compatibility Test

Drug should not be given to patients suffering from Kidney dysfunction, and Geriatrics.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.

Inf, Inj Store at room temperature, Between 15°C-30°C.

Do not administer dextran solution if any reaction occur. Urine output should be observed carefully.Intramuscular injection should not be administered to patient receiving dextran. Patient undergoing bowel surgery or who have pathalogical abdominal conditions and in case of sodium restriction should be treated cautiously with dextran. Dextran is classified as pregnancy category C and should be used during pregnancy only if clearly needed.