Dexamphetamine (Sulphate)

Dexamphetamine (Sulphate) used in the treatment of nacrolepsy and as an adjunct in the management of hyperactivity disorders in childrens (above the age of 6 years).


Brands
Adult Dose
Dose: 0.024 to 0.285 mg/kg
Single Dose: 0.15 (0.1545)
Frequency: 8 hourly
Route: PO
Instructions: As Required
Neonatal
Paedriatic
Dose: 5 mg
Single Dose: 5 (5)
Frequency: As recommended.
Route: Hyperactivity dose may be increased by 5mg at weekly intervals to upper limity of 20mg & 40mg in chi
Instructions:
Characteristics
Dexamphetamine (Sulphate) also known as Dexamfetamine (Sulphate), Dexamfetamine (Sulphate). . It is of Synthetic origin and belongs to Phenylethylamine. It belongs to Amine release pharmacological group on the basis of mechanism of action and also classified in CNS Stimulant pharmacological group.The Molecular Weight of Dexamphetamine (Sulphate) is 368.50. Its pKa is 9.9.
Contraindications
Dexamphetamine (Sulphate) is contraindicated in conditions like Angina,Diabetes mellitus,Glucoma,Hypertension,Hyperthyroidism,Insomnia,Anorexia,Psychopathic personality,Gille de la tourette syndrome,Cardiovascular disease,Dyskinesia.
Effects
The severe or irreversible adverse effects of Dexamphetamine (Sulphate), which give rise to further complications include Hallucinations, Hallucinations, Hypertension, Arrythmia.Dexamphetamine (Sulphate) produces potentially life-threatening effects which include Intracranial hemorrhages, Acute Renal Failure, Intracerebral bleeding, Acute renal failure. which are responsible for the discontinuation of Dexamphetamine (Sulphate) therapy.The symptomatic adverse reactions produced by Dexamphetamine (Sulphate) are more or less tolerable and if they become severe, they can be treated symptomatically, these include Headache, Irritability, Anorexia, Palpitation, Tachycardia, Insomnia, Nervousness, Abdominal pain, Sweating, Sleep disturbancesX, Blurred vision, Weight LossX, Weight loss, Dysphoria, Mydriasis, nervousness, Nervousness.
Indications
Dexamphetamine (Sulphate) is primarily indicated in conditions like Attention deficit disorders, Narcolepsy.
Interactions
Dexamphetamine (Sulphate) is known to interact with other drugs, the details of drug interactions is as follows:DrugDetailsSeverityOnsetManagementAdrenalineAlcoholChlorpromazine (HCl)Dipipanone (HCl)EthosuximideGuanethidineHaloperidolLithiumMetoprolol (Tartrate)MorphineMorphinePapaveretumPhenobarbitonePhenytoin (Na)PrazosinPropranolol (HCl) These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Interfrence
Risks
Drug should not be given to Paediatrics, Pregnant Mothers, Cardiac / Hypertensive Patients, Geriatrics, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
Tab Store at room temperature.
Warnings
Dexamphetamine should not be used in patients with cardiovascular disease including moderate to severe hypertension, hyperthydoidism, glaucoma, hyperexcitiability, agitated state, history of drug abuse. It is not recommended to use during pregnancy or lactation. It should be used with caution in patients with mild hypertension, impaired kidney function, epilepsy or unstable personality. Weight and height in children should be monitored as growth retardation may occur. Prolonged high dose may need gradual withdrawl as abrupt withdrawl may produce fatigue or mental depression.
Back to List

Any information that appears on this website page is provided for the purpose of general information. This website has been compiled in good faith by HMIS.Online. However, no guarantee is made as to the completeness, validity or accuracy of the information it contains.