Nitazoxanide

Nitazoxanide is antiprotozoal agent. Chemically, nitazoxanide is 2-acetyloxy-N-(5-nitro-2-thiazolyl)benzamide. The molecular formula is C12H9N3O5S.


Adult Dose
Dose: 500 to 500 mg
Single Dose: 500 (500)
Frequency: 12 hourly
Route: PO
Instructions: Take with food for three days.
Neonatal
Paedriatic
Dose: 100 mg
Single Dose: 100 (100)
Frequency: 12 hourly
Route: For 3 days in those aged 1 to 3 years
Instructions:
Characteristics
Nitazoxanide also known as Nitazoxanidum, Nitazoxanidum. . It is of Synthetic origin and belongs to nitrothiazolyl-salicylamide derivative. It belongs to Antidiarrhoeals and Antiprotozoal pharmacological group.The Molecular Weight of Nitazoxanide is 307.30.
Contraindications
Nitazoxanide is contraindicated in conditions like Hypersensitivity to the drug,Hypersensitivity to any component of product.
Effects
The severe or irreversible adverse effects of Nitazoxanide, which give rise to further complications include Allergic reactions.The symptomatic adverse reactions produced by Nitazoxanide are more or less tolerable and if they become severe, they can be treated symptomatically, these include Flatulence, Dizziness, Headache, Nausea, Vomiting, Diarrhea, Abdominal pain, Discoloration of urine, dizziness, Discoloration of eyes.
Indications
Nitazoxanide is primarily indicated in conditions like Diarrhea caused by Cryptosporidium parvum, Diarrhea caused by Giardia lamblia, HIV infection.
Interactions
No data regarding the interactions of Nitazoxanide was found.
Interfrence
Risks
Drug should not be given to Pregnant Mothers, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
tablet Store Between 15°C-30°C. Suspension Store in a well closed container, Between 15°C-30°C.
Warnings
Nitazoxanide must be administered with caution to patients with hepatic and bilary diseases, to patients with renal diseases, and to patients with combined renal and hepatic disease. It is not known whether nitazoxanide is excreted in human milk. Because many drugs are excreted in human milk, caution should be exercised when nitazoxanide is administered to a nursing women.
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