Nepafenac

Nepafenacis a topical sterile. It is an NSAID prodrug for ophthalmic use. It is a prodrug of amfenac.


Adult Dose
Dose: 1 drop
Single Dose: 1 (1)
Frequency: 8 hourly
Route: Opthalmic
Instructions: Start administration before one day to cataract surgery continue it on the day of surgery and for two weeks after surgery.
Neonatal
Paedriatic
Characteristics
belongs to Amino Benzoyl Benzeacetamide. . The Molecular Weight of Nepafenac is 254.28. It is weakly alkaline drug.
Contraindications
Nepafenac is contraindicated in conditions like Hypersensitivity.
Effects
The symptomatic adverse reactions produced by Nepafenac are more or less tolerable and if they become severe, they can be treated symptomatically, these include Headache, Photophobia, Tearing, Dry eye, Corneal edema, Vitreous detachment, Eye Pruritis, Ocular hyperemia, Capsular opacity, Conjunctival edema, Corneal edema, Lid margin crusting, Ocular discomfort, Ocular pain, Ocular pruritus.
Indications
Nepafenac is primarily indicated in conditions like Cataract surgery, Pain and inflammation.
Interactions
No data regarding the interactions of Nepafenac was found.
Interfrence
Risks
Drug should not be given to Paediatrics, Pregnant Mothers, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
Opthalmic Susp. Store Below 20°C.
Warnings
There is the potential for cross-sensitivity to acetylsalicylic acid, phenylacetic acid derivatives, and other nonsteroidal anti-inflammatory agents. Therefore, caution should be used when treating individuals who have previously exhibited sensitivities to these drugs. There exists the potential for increased bleeding time due to interference with thrombocyte aggregation. There have been reports that ocularly applied nonsteroidal anti-inflammatory drugs may cause increased bleeding of ocular tissues (including hyphemas) in conjunction with ocular surgery.
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