DESOFAM MARVELON

Dose: 150 mcg
Single Dose: 150 (150)
Frequency: 24 hourly
Route: PO
Instructions: Take regularly for 21 days followed by 7-day rest period after each month.

. It is of Synthetic origin and belongs to Steroid. It belongs to Progesterone agonist pharmacological group on the basis of mechanism of action and also classified in Sex Hormones and Contraceptive Oral pharmacological group.The Molecular Weight of Desogestrel is 310.50.

Desogestrel is contraindicated in conditions like Diabetes mellitus,Hypertension,Migraine,Thrombosis,Breast cancer,Vaginal bleeding,Systemic lupus erythematosus,Sickle cell anaemia,Circulatory system disease,Liver diseases,Otosclerosis,Atrial fibrillation,Hydatidiform mole,Valvular heart disease,Carcinoma of endometrium,Varicose veins,Porphyria,Disturbance of lipid metabolism.

The severe or irreversible adverse effects of Desogestrel, which give rise to further complications include Blindness, Hypertension, Blood clotting disorder, blockage of blood vessel, Double Vission, Heart Attack.Desogestrel produces potentially life-threatening effects which include Venous thromboembolism, Ischemic heart disease, Cerebrovascular disease, Venous thromboembolism, Cerebrovascular disease, Cerebrovascular stroke. which are responsible for the discontinuation of Desogestrel therapy.The signs and symptoms that are produced after the acute overdosage of Desogestrel include Nausea, Vomiting.The symptomatic adverse reactions produced by Desogestrel are more or less tolerable and if they become severe, they can be treated symptomatically, these include Headache, Nausea, Vomiting, Fluid retention, Breast tension, Changes in body weights, Depressive moods, Changes in libido, Amenorrhea, Migraine, Irregular bleeding, changes in libido.

Desogestrel is primarily indicated in conditions like Acne, Contraception, Hirsutism.

Desogestrel is known to interact with other drugs, the details of drug interactions is as follows:DrugDetailsSeverityOnsetManagementAscorbic AcidCarbamazepinePhenobarbitonePhenytoin (Na)PrimidoneRifampicinTegaserodTegaserod decreased Desogestrel plasma concentrations by less than 10% in a clinical study with a low-dose triphasic oral contraceptive (n=45). The mechanism is unknown. There were no changes in ethinyl estradiol concentrations or in contraceptive efficacy. No action is necessary.MinorTocopherol (Vitamin E)Desogestrel, Ethinyloestradiol and other destrogen when given with Tocopherol (Vitamin E) may increase the risk of thrombosis. These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

Urine tests for 17-ketosteroids and 17-OH-Corticosteroids & Aldosterone. Serum tests for adrenal corticosteroids. Thyopac Method for measurement of T-3 Levels.

Drug should not be given to Paediatrics, Pregnant Mothers, Geriatrics, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.

Tab Store Below 40°C. Protect from Sunlight and Moisture.

Desogestrel should be used with caution in patients with medical history, including family medical history, especially if have asthma, high blood pressure, kidney, liver or heart disease, history of jaundice (yellowing of skin or eyes) or high blood pressure during pregnancy, excessive weight gain or fluid retention during menstrual cycle, strokes, blood clots, heart attacks, seizures, migraine headaches, breast cancer, high blood level of cholesterol or lipids (fats) or depression.Higher strengths are more likely to cause melasma (darkening of skin), sunlight may intensify this darkening, so need to avoid prolonged sun exposure and sunlamps, consult the doctor regarding use of sunscreens and protective clothing.This medication must be discontinued if a women suspect to be pregnant. Avoid desogestrel during lactation. Birth-control pills slightly increase risk of strokes, blood clots, high blood pressure, heart attacks, gallbladder disease, vision problems and liver tumors.Cigarette smoking (especially 15 or more cigarettes daily) and age (women older than 35 or 40 years of age) further increase the risk of stroke, blood clots, high blood pressure and heart attacks. If patients are near-sighted or wear contact lenses, it may develop vision problems, also tolerance of the lenses may decrease, contact the eye doctor if these problems occur. Before having surgery, including dental surgery, tell the doctor about taking birth-control pills.