Insulin Lispro Protamine

'Insulin lispro protamine suspension (NPL component) is a suspension of crystals produced from combining insulin lispro and protamine sulfate under appropriate conditions for crystal formation. This medication is used to control blood sugar in patients with diabetes mellitus. Controlling high blood sugar helps prevent heart disease, strokes, kidney disease, blindness and circulation problems. It promotes glucose transport, which stimulates carbohydrate metabolism in skeletal and cardiac muscle and adipose tissue. Also promotes phosphorylation of glucose in liver, where it''s converted to glycogen. Directly affects fat and protein metabolism, stimulates protein synthesis, inhibits release of free fatty acids, and indirectly decreases phosphate and potassium. It is available in premixed form with insulin lispro in 75/25 and 50/50 ratio.'

Brands
HUMALOG MIX 25 HUMALOG MIX 25 HUMALOG MIX 50
Adult Dose
Dose: Sc
Single Dose:
Frequency:
Route:
Instructions:
Neonatal
Paedriatic
Characteristics
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Contraindications
Insulin Lispro Protamine
Effects
The symptomatic adverse reactions produced by Insulin Lispro Protamine are more or less tolerable and if they become severe, they can be treated symptomatically, these include Headache, Chills, Tingling of the hand, Hypoglycemia, Fainting.
Indications
Insulin Lispro Protamine is primarily indicated in conditions like Type I diabetes mellitus, Type II diabetes mellitus.
Interactions
No data regarding the interactions of Insulin Lispro Protamine was found.
Interfrence
Risks
If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
Store in a well closed container, Below 25°C. Refrigeration and Freezing is not recommended.
Warnings
its doses will vary among patients and should be determined by the healthcare provider familiar with the patient€™s metabolic needs, eating habits, and other lifestyle variablesThe dose of insulin lispro protamine when available in combination with insulin lispro (75/25 or 50/50 ratio) should be given within 15 minutes before a meal.
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