IMPAVIDO FOSINE

Dose: 2.5 mg/kg/day
Single Dose: 2.5 (2.5)
Frequency: As recommended.
Route: PO
Instructions: Should be given for 28 days.The dose should be adjusted based on patients weight so that a dose of 4mg/kg per day is not exceeded.

. It is of Synthetic origin and belongs to Phospholipid. It belongs to Antiprotozal Agent pharmacological group.The Molecular Weight of Miltefosine is 407.57.

Miltefosine is contraindicated in conditions like Pregnancy.

The symptomatic adverse reactions produced by Miltefosine are more or less tolerable and if they become severe, they can be treated symptomatically, these include Diarrhea, Nausea and vomiting, Hepatotoxicity.

Miltefosine is primarily indicated in conditions like Visceral leishmaniasis, and can also be given in adjunctive therapy as an alternative drug of choice in Colorectal cancer, Metastatic breast cancer.

No data regarding the interactions of Miltefosine was found.

Increased in Serum AminotransferaseIncreased level of Blood urea nitrogen (BUN) concentrationsIncreased in serum creatinin

Drug should not be given to Pregnant Mothers.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.

Precautions should be taken in Handling. Avoid contact with eyes, skin, and clothing. Should be use with caution in patients withwith advanced disease, breastfeeding women, HIV-infected patients, and individuals with significant renal or hepatic insufficiency.