Insulin Detemir

Insulin detemir is a long-acting human insulin analogue for maintaining the basal level of insulin. Insulin detemir differs from human insulin in that the amino acid threonine in position B30 has been omitted, and a C14 fatty acid chain has been attached to the amino acid B29.


Brands
Adult Dose
Dose:
Single Dose:
Frequency:
Route:
Instructions: For patients treated with glucose detimer once-daily, the dose should be administered with the evening meal or at bedtime. _x000D_For patients who require twice-daily dosing for effective blood glucose control, the evening dose can be administered either with the evening meal, at bedtime, or 12 hours after the morning dose._x000D_
Neonatal
Paedriatic
Characteristics
. It is of Natural origin. It belongs to Insulin agonist pharmacological group on the basis of mechanism of action and also classified in Antidiabetic Agent, Insulin pharmacological group.The Molecular Weight of Insulin Detemir is 5916.90.
Contraindications
Insulin Detemir is contraindicated in conditions like Hypoglycaemia,Hypersensitivity to the drug.
Effects
The severe or irreversible adverse effects of Insulin Detemir, which give rise to further complications include Rashes, Wheezing, Sweating, Blurred vision.Insulin Detemir produces potentially life-threatening effects which include Shortness of breath. which are responsible for the discontinuation of Insulin Detemir therapy.The signs and symptoms that are produced after the acute overdosage of Insulin Detemir include Coma, Seizures, Hypoglycemia.The symptomatic adverse reactions produced by Insulin Detemir are more or less tolerable and if they become severe, they can be treated symptomatically, these include Allergic reactions, Weight gain, Hypersensitivity, lipodystropy.
Indications
Insulin Detemir is primarily indicated in conditions like Type I diabetes mellitus, Type II diabetes mellitus.
Interactions
No data regarding the interactions of Insulin Detemir was found.
Interfrence
Monitoring of blood and urine glucose
Risks
If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
Inj Store Below 15°C. Do not Freeze.
Warnings
Glucose should be regularly monitored in all patients with diabetes. Glucose detimer is not to be used in insulin infusion pumps. Tell your doctor if you have or have ever had nerve damage caused by your diabetes, liver or kidney disease. If you are having surgery, including dental surgery, tell the doctor or dentist that you are using insulin detemir.
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