NYSA XEGTIN ELEVER FELBEX OTEK OTTOXIM PIREXEN PIREXEN PIROGESIC WNSECAM BETACARE SHAZITOX BETAGREEN ANTIXIN P-CYCLO MORKIL CAPIROX PAINZA PYZED PELDIN BEXICAM PIROXIADVAN EXIN PEEDEX BETACAM BECAM TRIXIN PIRET PIROMED BRIXTON CYCLOTRIN MEDROX-C NOAXIN PIROXIM-NEO RELEVO X-CAM BARQ BCD BETACAM LOCAM PLUS MEJIC ORTHOLIVE P P.B PAINGUIN PIROWAN PLUS PYRIN CYCLORAM HARRICAM INFLADEX INFLADEX PIRAM-BX PIROPULSE BREXOL DETACAM PIROMAK REGAM WOXICAM ZEECAM TABLET PIROXIBIN OREXIN IROWEL FLAGESIC EREXIN OXIDEX BREXIDOL NEFAM BETA-1 BOSHCAM-B PBC PEXTRIN ROXBET BETA-20 BETA-20 betoxi BEWEL BREXICAM CAMTRIN GEOFTRIN MUTEX NOATRIN

Dose: 10 to 20 mg
Single Dose: 15 (15)
Frequency: 1 hourly
Route: IM
Instructions: For orthopedic surgery administer 40 mg OD for 2 days followed by 20 mg OD

Piroxicam-beta-cyclodextrin also known as . . It is of Synthetic origin and belongs to Oxicam. It belongs to Cyclo-oxygenase inhibitor pharmacological group on the basis of mechanism of action. The Molecular Weight of Piroxicam-beta-cyclodextrin is 331.40. Its pKa is 6.3.

Piroxicam-beta-cyclodextrin is contraindicated in conditions like Asthma,Peptic ulcer,Thrombosis,Rhinitis,Urticaria,Impaired hepatic function,Hypersensitivity,Angioedema.

The severe or irreversible adverse effects of Piroxicam-beta-cyclodextrin, which give rise to further complications include Skin reactions, Erythema, Interstitial nephritis.Piroxicam-beta-cyclodextrin produces potentially life-threatening effects which include GI bleeding, Aplastic Anemia, Renal damage, Peptic ulceration, Purpura, Pemphigus vulagris. which are responsible for the discontinuation of Piroxicam-beta-cyclodextrin therapy.The signs and symptoms that are produced after the acute overdosage of Piroxicam-beta-cyclodextrin include Nausea, Vomiting, Diarrhea, Convulsions, Coma, Hematuria, Acute renal failure, Dizziness, Headache, Hyperventilation, Rashes, Proteinuria, Hyperreflexia, Tinnitus, Hypoprothrombinemia, GI bleeding, hyper reflexia.The symptomatic adverse reactions produced by Piroxicam-beta-cyclodextrin are more or less tolerable and if they become severe, they can be treated symptomatically, these include Diarrhea, Skin irritation, Nausea and vomiting, Edema, GI disturbance, Erythema multiforme, Azotemia, bronchoconstriction.

Piroxicam-beta-cyclodextrin is primarily indicated in conditions like Acute gout, Acute musculoskeletal disorders, Acute pain, Ankylosing spondylitis, Backache, Dysmenorrhoea, Juvenile chronic arthritis, Migraine, Osteoarthritis, Post operative pain, Rheumatic diseases, and can also be given in adjunctive therapy as an alternative drug of choice in Juvenile rheumatoid arthritis.

No data regarding the interactions of Piroxicam-beta-cyclodextrin was found.

Auditory function test

Drug should not be given to Pregnant Mothers, patients suffering from Liver Malfunction, Geriatrics, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.

Piroxicam should be used with caution in patients with intrinsic coagulation defects and those on anticoagulant therapy. It should be used with caution in patients with compromised cardiac function, hypertension other condition predisposing to fluid retention. Discontinue drug if skin reaction occurs. It should be used with extra care in the presence of existing controlled infection.