Magnesium

A light, silvery-white, moderately hard metallic element that in ribbon or powder form burns with a brilliant white flame. It is used in structural alloys, pyrotechnics, flash photography, and incendiary bombs,occurs naturally only in combination.Atomic number 12; atomic weight 24.305; melting point 649°C; boiling point 1,090°C; specific gravity 1.74 (at 20°C); valence 2.


Adult Dose
Dose: 10 to 20 m mol
Single Dose: 15 (15)
Frequency: 24 hourly
Route: IV
Instructions: For Substitution for pregnant risk patients: Initial loading dose
Neonatal
Paedriatic
Characteristics
. It is of Natural origin. . The Molecular Weight of Magnesium is 24.30.
Contraindications
Magnesium is contraindicated in conditions like Renal failure,Atrioventricular block.
Effects
The signs and symptoms that are produced after the acute overdosage of Magnesium include Hypotension, Flushing, Respiratory arrest, Cardiac arrest, tendon reflexes, Hypermangnesemia.The symptomatic adverse reactions produced by Magnesium are more or less tolerable and if they become severe, they can be treated symptomatically, these include Thirst, Diarrhea, Abdominal cramps, Confusion, Nausea and vomiting, Confusion, Slurred vision.
Indications
Magnesium is primarily indicated in conditions like Hypomagnesaemia, and can also be given in adjunctive therapy as an alternative drug of choice in Myocardial infarction, Ventricular tachycardia.
Interactions
Magnesium is known to interact with other drugs, the details of drug interactions is as follows:DrugDetailsSeverityOnsetManagementDisodium PamidronateDolutegravirdecreases level of dolutegravirshould be administered 2hrs before or 6hrs after taking medication containing magnesiumTetracycline (HCl) These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Interfrence
Risks
Drug should not be given to Cardiac / Hypertensive Patients, patients suffering from Kidney dysfunction, patients suffering from Liver Malfunction, Geriatrics, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
Warnings
Diabetes patients must be cautious of the sugar contained in several magnesium preparations.Should be given with caution in renal impairment and myesthenia gravis.
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