ACSOLVE BEZCLIN CLINDA V JALACIN JALACIN CALINAX VAGIBACT CLIMACIN-V CLINDAMAX DUPEARL DALACIN-V DALACIN-T DALACIN-C DALACIN-C DALACIN-C DALACIN-C DALACIN-C CLINDACIN GEL CLINDAMYCIN CLINDAMYCIN CLYCIN-V CLYCIN-V CLYCIN-T DUAC DUAC CLINAGEL CLERET AUSTACLIN-T BENCLIN SAFEBACT CLINDA T ACNIPHOS ACNIPHOS-V CLINDA PLUS CLINDA DERM CLINDA DERM CLINDA CLINDA CLINXER LAWRMYCIN CLEOCIN CLEOCIN CLEOCIN CLYAIM V ACNEKLIN VECLIN CYINE CYINE DAYMAC CLIMED-V KLINDA KLINDA VEGACIN BENDUE BENDUE KLENCIN KLENCIN KLENCIN LEDERBACT V CLINDATOS-B CLING CLING CLINZEN MAGACIN CLINDATE CLINDACIN CAPSULE HODACIN CLINDEX MYCIN MYCIN GREENLIN-150 GREENLIN-300 CALIDIN CALIDIN ACNEMYCIN V ACNEMYCIN V CALINOL-V CALINOL PLUS LIN-CLID CLIMAX-V BENWAC BENWAC CLINACIN KLINDA-CAP

Dose: 300 to 600 mg
Single Dose: 450 (450)
Frequency: 6 hourly
Route: IM, IV
Instructions: Should not Exceed 4.8g/day

Dose: 8 to 16 mg/kg
Single Dose: 12 (12)
Frequency: 6 hourly
Route: serious infection
Instructions:

Clindamycin (HCl), Clindamycin (HCl) are the derivatives of Clindamycin. It is of Semi Synthetic origin and belongs to Deoxylincomycin. It belongs to Antibacterial (Proetin synthesis inhibitor) pharmacological group on the basis of mechanism of action and also classified in Antibiotics pharmacological group.The Molecular Weight of Clindamycin is 479.50. It is weakly acidic drug, 10.73% solution of the drug is isotonic and Its pKa is 7.7.

Clindamycin is contraindicated in conditions like Pseudomembranous colitis,Hypersensitivity.

The severe or irreversible adverse effects of Clindamycin, which give rise to further complications include Elevated SGPT & SGOT, Elevated alkaline phosphatase concentration, Esophageal ulceration, Severe diarrhea.Clindamycin produces potentially life-threatening effects which include Ventricular fibrillation, Anaphylactic shock, Pseudomembranous colitis, Cardiac Arrest, Colonic ulceration, Mucosal edema. which are responsible for the discontinuation of Clindamycin therapy.The symptomatic adverse reactions produced by Clindamycin are more or less tolerable and if they become severe, they can be treated symptomatically, these include Nausea, Vomiting, Abdominal pain, Rashes, Vaginitis, Contact dermatitis, Leukocytoclastic angiitis, Local irritation, Reaction at injection site, Xerosis, Cervicitis.

Clindamycin is primarily indicated in conditions like Acne vulgaris, Babesiosis, Bacterial infections, Bacterial vaginosis, Dental infections, Endocarditis, Hidradenitis suppurativa, Intra-abdominal infections, Malaria, Osteomyelitis, Pelvic infections, Peritonitis, Pulmonary infection, Septic arthritis, Septicaemia, Soft tissue infections, Staphylococcal bone and joint infections, Systemic sepsis, Toxoplasmosis.

Clindamycin is known to interact with other drugs, the details of drug interactions is as follows:DrugDetailsSeverityOnsetManagementAmikacin (Sulphate)BamifyllineCalcium GluconateChlorocarbacholDistigmine (Br)GentamicinKaolinPectin suspensionLincomycin (HCl)Pancuronium (Br)PhysostigmineRivastigmineRocuronium (Br)Sodium ThiosulphateConcomitant use may result in excessive irritation or drying. Moderate These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

Liver Function Test (LFT)

Drug should not be given to Pregnant Mothers, patients suffering from Kidney dysfunction, patients suffering from Liver Malfunction, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.

Store Below 30°C.

Clindamycin should be used with caution in patients with kidney or liver impairments and gastrointestinal diseases. Take appropriate measures in case of secondary infections.