Nandrolone

Nandrolone is an anabolic steroid with some androgenic properties. It is a sex hormone, with actions and adverse effects similer to testosterone. Chemically itis 17β-[(1-oxodecyl) oxy] ester-4-en-3-one. It has androgenic,progestogenic and erythropoietic activity, but anabolic effects greater than androgenic effects. Used in treatment of debilitating illness and carcinoma of the breast. Its derivative Nandrolone (Decanoate) is given only through parentrally, not active when given orally. Nandrolone sodium sulfate has been used topically in the treatment of corneal damage.

Brands
ABOLON DECABOLIN DECABOLIN DEKA-DURALIN DECA-DURABOLIN DECA-DURABOLIN DECA-DURABOLIN DURABOLIN
Adult Dose
Dose: 25 to 100 mg
Single Dose: 62 (62.5)
Frequency: As recommended.
Route: IM
Instructions: Once every week.
Neonatal
Paedriatic
Characteristics
Nandrolone also known as Nortestosterone Phenylpropionate. Nandrolone (Decanoate), Nandrolone (Decanoate) are the derivatives of Nandrolone. It is of Synthetic origin and belongs to Steroid. It belongs to Aldosterone agonist pharmacological group on the basis of mechanism of action and also classified in Sex Hormones and Anabolic Steroid pharmacological group.The Molecular Weight of Nandrolone is 274.10.
Contraindications
Nandrolone is contraindicated in conditions like Prostatic cancer,Male breast carcinoma.
Effects
The severe or irreversible adverse effects of Nandrolone, which give rise to further complications include Deepening of voice, Stunting growth in children, liver Tumor.Nandrolone produces potentially life-threatening effects which include Atherosclerosis. which are responsible for the discontinuation of Nandrolone therapy.The signs and symptoms that are produced after the acute overdosage of Nandrolone include Increased low density lipo-protein, Azoo-spermia, Increased fibrinolytic activity.The symptomatic adverse reactions produced by Nandrolone are more or less tolerable and if they become severe, they can be treated symptomatically, these include Headache, Depression, Edema, Acne, Abnormal LFT, Facial hair, Clitoromegaly, Menstrual irregularity, Increase in libido, Temporal recession of scalp hair, Hypercalcemia, Sodium and fluid retention, GI bleeding, Impaired glucose tolerance, Abnormal LFT, inhibition of spermatagnesis.
Indications
Nandrolone is primarily indicated in conditions like Anaemia, Aplastic anemia, Breast cancer, Corneal infection, Corneal injury, Corneal ulcers, Osteoporosis, and can also be given in adjunctive therapy as an alternative drug of choice in Chronic debilitating disease, Renal failure, Surgery.
Interactions
No data regarding the interactions of Nandrolone was found.
Interfrence
Risks
Drug should not be given to Pregnant Mothers, Cardiac / Hypertensive Patients, patients suffering from Kidney dysfunction, patients suffering from Liver Malfunction, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
Inj Store Below 25°C. Protect from Sunlight.
Warnings
Nandrolone decanoate should be used with caution in patients with any disease, especially cancer of the prostate or breast, liver, heart, kidney disease, allergy, enlarged prostate. High dosage, long term use of androgens has been related to liver cancer. This drug should not be used during pregnancy or lactation. Females should be monitored for signs of virilization, such as deepening of the voice, facial hair, acne, menstrual irregularity or clitoral enlargement, consult the doctor promptly if any of these symptoms occur. Use in children should not be recommended due to the possibility this drug may have undesirable effects related to the growth of the child. It should be used with extreme caution in geriatric men because they are at higher risk for developing enlarged prostates or prostate cancer when using this medication. Warninigs and precautions should be considered in patients with cardiac insufficiency, arterial hypotension, nephrotic syndrom, sportsmen.
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