Methacholine Chloride

Methacholine chloride is a slowly hydrolyzed muscuranic agonist.It is used as parasympathomimetic bronchoconstrictor agent and as a diagnostic aid for bronchial asthma.

Brands
Adult Dose
Neonatal
Paedriatic
Characteristics
. It is of Synthetic origin and belongs to Queternary ammonium. . The Molecular Weight of Methacholine Chloride is 195.70.
Contraindications
Methacholine Chloride is contraindicated in conditions like Asthma,Urinary obstruction.
Effects
The severe or irreversible adverse effects of Methacholine Chloride, which give rise to further complications include Bradycardia.The symptomatic adverse reactions produced by Methacholine Chloride are more or less tolerable and if they become severe, they can be treated symptomatically, these include Headache, Diarrhea, Sweating, Nausea and vomiting, Salivation.
Indications
Methacholine Chloride can be given in adjunctive therapy as an alternative drug of choice in Glaucoma, Raynaud`s syndrome.
Interactions
No data regarding the interactions of Methacholine Chloride was found.
Interfrence
Risks
Drug should not be given to Paediatrics, Pregnant Mothers, Cardiac / Hypertensive Patients, patients suffering from Kidney dysfunction, patients suffering from Liver Malfunction, Geriatrics, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
Store in a well closed container.
Warnings
Methacholine has the potential to produce severe bronchocostriction and it should be used for inhalation challenge test in pateint with clinically appasent asthma,wheezing or poor pulmonary function. It should be given orally or paunctually.
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