Dipivefrine

Dipivefrine (HCl) is a prodrug metabolized to adrenaline. Dipivefrine (HCl) is used topically as eye drops to reduce intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension, where the prodrug passes through the cornea more readily than adrenaline.

Brands
PROPINE
Adult Dose
Dose: Apply every 12 hours.
Single Dose:
Frequency:
Route:
Instructions:
Neonatal
Paedriatic
Characteristics
Dipivalyl Adrenaline (HCl), Dipivalyl Adrenaline (HCl) are the derivatives of Dipivefrine. It is of Synthetic origin and belongs to Ester. . The Molecular Weight of Dipivefrine is 351.40.
Contraindications
Dipivefrine is contraindicated in conditions like Hypersensitivity.
Effects
The severe or irreversible adverse effects of Dipivefrine, which give rise to further complications include Photosensitivity, Headache, Eye irritation, Blurred vision, Eye pain.The symptomatic adverse reactions produced by Dipivefrine are more or less tolerable and if they become severe, they can be treated symptomatically, these include Tachycardia, Irregular heart beat, Chest pain, Wheezing.
Indications
Dipivefrine is primarily indicated in conditions like Glaucoma, Ocular hypertension, Open-angle glaucoma.
Interactions
No data regarding the interactions of Dipivefrine was found.
Interfrence
Risks
If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
Warnings
Care should be taken in allergic patients. If you are using other eye drops,use them 10 min apart. Donot touch the dropper.
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