Prajmalium Bitartarate

Prajmalium bitartarate is a class I antiarrythmic and is N-propyl derivative of Ajmaline.


Brands
Adult Dose
Dose: 60 to 80 mg
Single Dose: 70 (70)
Frequency: As recommended.
Route: oral
Instructions: maintainance dose of 20-40 mg per day in divided doses should be given.
Neonatal
Paedriatic
Characteristics
. The Molecular Weight of Prajmalium Bitartarate is 518.60.
Contraindications
Prajmalium Bitartarate is contraindicated in conditions like Hypersensitivity,Pregnancy,Cardiogenic shock in infarction/cardiac surgery.
Effects
The severe or irreversible adverse effects of Prajmalium Bitartarate, which give rise to further complications include Convulsions, Coma, Agranulocytosis, Respiratory depression.The signs and symptoms that are produced after the acute overdosage of Prajmalium Bitartarate include Cardiac arrhythmias, Unconsciousness, Heart block.The symptomatic adverse reactions produced by Prajmalium Bitartarate are more or less tolerable and if they become severe, they can be treated symptomatically, these include Headache, Nausea, Constipation, Loss of appetite.
Indications
Prajmalium Bitartarate is primarily indicated in conditions like Acute myocardial infarction, Supraventricular arrhythmias, and can also be given in adjunctive therapy as an alternative drug of choice in Tachycardia.
Interactions
No data regarding the interactions of Prajmalium Bitartarate was found.
Interfrence
Risks
Drug should not be given to Pregnant Mothers.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
Warnings
Prajmalium bitartarate should be used with caution in patients with heart block. Care should be taken in myesthenia gravis patients. Reduced dosage should be given to elderly patients.
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