Cyproheptadine (HCl)

Cyproheptadine is a serotonin and histamine antagonist with anticholinergic and sedative properties, resembles the phenothiazine antihistaminic agents in chemical structure and has potent H1 receptor blocking actions.


Adult Dose
Dose: 4 to 8 mg
Single Dose: 6 (6)
Frequency: 8 hourly
Route: PO
Instructions: It may be given 4 times daily.
Neonatal
Paedriatic
Dose: 0.2 to 4 mg/kg
Single Dose: 2.1 (2.1)
Frequency: 8 hourly
Route: Oral
Instructions: -
Characteristics
Epidroheptadine, Epidroheptadine, Epidroheptadine, Epidroheptadine, Epidroheptadine, Epidroheptadine, Epidroheptadine are the derivatives of Cyproheptadine (HCl). It is of Synthetic origin and belongs to Benzopiperidine. It belongs to H2 and 5HT antagonist pharmacological group on the basis of mechanism of action. The Molecular Weight of Cyproheptadine (HCl) is 350.90.
Contraindications
Cyproheptadine (HCl) is contraindicated in conditions like Asthma,Glucoma,Prostatism,Pyloric stenosis.
Effects
The severe or irreversible adverse effects of Cyproheptadine (HCl), which give rise to further complications include Tachycardia, Hypotension, Psychiatric disturbances, Hypotension, Neurological disturbances, Palpitation, Urinary retention, Wheezing, Nasal blockage, GI upsets, Difficulties in micturition, Urinary retention.Cyproheptadine (HCl) produces potentially life-threatening effects which include Blood dyscrasias, Hepatitis, Anaphylactic reactions. which are responsible for the discontinuation of Cyproheptadine (HCl) therapy.The signs and symptoms that are produced after the acute overdosage of Cyproheptadine (HCl) include Vomiting, Convulsions, Hallucinations, Ataxia, CNS depression.The symptomatic adverse reactions produced by Cyproheptadine (HCl) are more or less tolerable and if they become severe, they can be treated symptomatically, these include Drowsiness, Fatigue, Nausea, Dry mouth, Weight gain, Increased appetite, Dry mouth.
Indications
'Cyproheptadine (HCl) is primarily indicated in conditions like Acromegaly, Advanced ovarian cancer, Angioedema, Anorexia nervosa, Antidepressant-induced inorgasmia, Appetite stimulation, Carcinoid syndrome, Cushing''s syndrome, Hyperprolactinaemia, Migraine, Nelsons syndrome, NSAID associated ulceration, Pruritus, Symptomatic relief of allergy, To prevent recurrence of neural tube defect, Urticaria, Vascular headaches, and can also be given in adjunctive therapy as an alternative drug of choice in Severe nausea, vomiting (prevention).'
Interactions
Cyproheptadine (HCl) is known to interact with other drugs, the details of drug interactions is as follows:DrugDetailsSeverityOnsetManagementAlcoholChloroquineProtirelin These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Interfrence
Risks
Drug should not be given to Pregnant Mothers, Geriatrics, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
Tab Store in a well closed container, . Protect from Sunlight and Moisture.
Warnings
Cyproheptadine should be used with caution in bone marrow depression. Patients should observe caution while driving or performing other task requiring alertness because it may cause drowsiness. It should be used with caution in patients with urinary retention, history of bronchial asthma, hyperthyroidism, cardiovascular or liver disease. It should be used with caution in person with acute or chronic respiratory impairment, especially in children. Do not administer subcutaneously because irritation or lesion may occur.
Back to List

Any information that appears on this website page is provided for the purpose of general information. This website has been compiled in good faith by HMIS.Online. However, no guarantee is made as to the completeness, validity or accuracy of the information it contains.