Polyestradiole Phosphate

Polyestradiol phosphate is a polymer of estradiole which has prolong duration of action and is used in treatment of metastatic prostatic carcinoma.

Brands
Adult Dose
Dose: 80 to 160 mg
Single Dose: 120 (120)
Frequency: As recommended.
Route: IM
Instructions: Dose should be decreased upto 40-80mg and should be given every 4 weeks by maintainance.
Neonatal
Paedriatic
Characteristics
belongs to ester. . The Molecular Weight of Polyestradiole Phosphate is 370.38.
Contraindications
Polyestradiole Phosphate
Effects
The severe or irreversible adverse effects of Polyestradiole Phosphate, which give rise to further complications include Cholestatic jaundice, Impotence, Gynacomastia, Venous thrombosis.The signs and symptoms that are produced after the acute overdosage of Polyestradiole Phosphate include Bone pain, Hypercalcemia.The symptomatic adverse reactions produced by Polyestradiole Phosphate are more or less tolerable and if they become severe, they can be treated symptomatically, these include Nausea, Skin reactions, Fluid retention.
Indications
Polyestradiole Phosphate is primarily indicated in conditions like Metastatic carcinoma.
Interactions
No data regarding the interactions of Polyestradiole Phosphate was found.
Interfrence
Risks
If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
Warnings
Polyestradiole phosphate should be used with caution in children because of premature epiphyser closure.
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