Propiomazine

Propiomazine is an a typical antipsychotic used to treat -ve and +ve symptoms of shizophrenia.It is a phenothiazine derivative and is a sedating antihistamine used for its sedative and antiemetic properties in insomnia.


Brands
Adult Dose
Dose: 25 to 50 mg
Single Dose: 38 (37.5)
Frequency: As recommended.
Route: oral
Instructions:
Neonatal
Paedriatic
Characteristics
. The Molecular Weight of Propiomazine is 340.48.
Contraindications
Propiomazine is contraindicated in conditions like Hypersensitivity,Neonates.
Effects
The severe or irreversible adverse effects of Propiomazine, which give rise to further complications include Convulsions, Fever, Urinary retention, Sweating, Blood disorders, Irregular heart beat, Psychomotor impairment.The signs and symptoms that are produced after the acute overdosage of Propiomazine include Convulsions, fatigue, Dry mouth, Ataxia, Excitation, Myalgia, difficulty in breathing.The symptomatic adverse reactions produced by Propiomazine are more or less tolerable and if they become severe, they can be treated symptomatically, these include Dizziness, Headache, Drowsiness, Diarrhea, Blurred vision, Skin rash, Nausea and vomiting, Lassitude.
Indications
Propiomazine is primarily indicated in conditions like Agitation, Insomnia, Mania, Schizophrenia, and can also be given in adjunctive therapy as an alternative drug of choice in Anxiety, Dementia, Labor, Nausea and vomiting.
Interactions
No data regarding the interactions of Propiomazine was found.
Interfrence
False +ve phentolamine test
Risks
Drug should not be given to Geriatrics, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
Warnings
Cautions should be taken in patients with epilepsy. It excreted in form of active metabolite in urine so dosage reduction may be necessary in renal impairement. Donot drive because it may produce drowziness. Avoid alcohol.
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