Paregoric

Paregoric, or camphorated tincture of opium, is a medication known for its antidiarrheal, antitussive, and analgesic properties. It was a household remedy in the 18th and 19th centuries, when it was widely used to calm fretful children.


Brands
Adult Dose
Dose: 5 to 10 ml
Single Dose: 7.5 (7.5)
Frequency: As recommended.
Route: PO
Instructions: 1-4 times daily.
Neonatal
Paedriatic
Characteristics
.
Contraindications
Paregoric is contraindicated in conditions like Convulsions,Tetanus,Hypersensitivity to any component of product.
Effects
The severe or irreversible adverse effects of Paregoric, which give rise to further complications include Pruritis, Constipation.The signs and symptoms that are produced after the acute overdosage of Paregoric include Bradycardia, Hypotension, Death, Apnea, Coma, Respiratory depression, Respiratory depression, Cardiac arrest, Dysphoria, Somnolence, Euphoria.The symptomatic adverse reactions produced by Paregoric are more or less tolerable and if they become severe, they can be treated symptomatically, these include Dizziness, Sedation, Nausea and vomiting, Light headedness.
Indications
Paregoric is primarily indicated in conditions like Diarrhoea.
Interactions
No data regarding the interactions of Paregoric was found.
Interfrence
Risks
Drug should not be given to Pregnant Mothers, patients suffering from Kidney dysfunction, patients suffering from Liver Malfunction, and Geriatrics.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
Store in a well closed container, at room temperature. Protect from Sunlight and Moisture.
Warnings
Paregoric should be used with extreme caution in patients with disorders characterized by hypoxia, since even usual therapeutic doses of narcotics may decrease respiratory drive to the point of apnea while simultaneously increasing airway resistance. Because of a possible vagolytic action that may produce a significant increase in the ventricular response rate, Paregoric should be used with caution in patients with atrial flutter and other supraventricular tachycardias. Paregoric appears in the milk of nursing mothers. Caution should be exercised when paregoric is administered to a nursing woman. Animal reproduction studies have not been conducted with morphine. It is not known whether morphine can cause fetal harm when administered to a pregnant woman or can affect reproduction capacity. Paregoric should be given to a pregnant woman only if clearly needed. This preparation should not be used in diarrhea caused by poisoning until the toxic material is eliminated from the gastrointestinal tract.
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