Oxymetholone

Oxymetholone, is a synthetic anabolic steroid used in the treatment of anemia and for the prophylaxis and treatment of hereditary angioedema.


Brands
Adult Dose
Dose: 1 to 5 mg/kg
Single Dose: 3 (3)
Frequency: As recommended.
Route: PO
Instructions: Daily.
Neonatal
Paedriatic
Characteristics
. It is of Synthetic origin. . The Molecular Weight of Oxymetholone is 332.50.
Contraindications
Oxymetholone is contraindicated in conditions like Hypercalcaemia,Breast cancer,Hepatic dysfunction,Hypersensitivity,Prostate cancer.
Effects
The severe or irreversible adverse effects of Oxymetholone, which give rise to further complications include Hepatitis, Insomnia, Liver cirrhosis.The symptomatic adverse reactions produced by Oxymetholone are more or less tolerable and if they become severe, they can be treated symptomatically, these include Diarrhea, Nausea and vomiting, Acne, Bloating, Clitoral hypertrophy.
Indications
Oxymetholone is primarily indicated in conditions like Anaemia, Aplastic anemia.
Interactions
No data regarding the interactions of Oxymetholone was found.
Interfrence
Glucose Tolerance Test Abnormal LFTs Serum Triglycerides Measurement.
Risks
Drug should not be given to Pregnant Mothers, patients suffering from Kidney dysfunction, and patients suffering from Liver Malfunction.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
Warnings
Women should be observed for signs of virilization (deepening of the voice, hirsutism, acne and clitoromegaly). To prevent irreversible change, drug therapy must be discontinued when mild virilism is first detected. Such virilization is usual following androgenic anabolic steroid use at high doses. Some virilizing changes in women are irreversible even after prompt discontinuance of therapy and are not prevented by concomitant use of estrogens. Menstrual irregularities, including amenorrhea, may also occur. The insulin or oral hypoglycemic dosage may need adjustment in diabetic patients who receive anabolic steroids. Concurrent dosing of an anabolic steroid and warfarin may result in unexpectedly large increases in the INR or prothrombin time (PT). When an anabolic steroid is prescribed to a patient being treated with warfarin, doses of warfarin may need to be decreased significantly to maintain the desirable INR level and diminish the risk of potentially serious bleeding.
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