Oxandrolone

Oxandrolone is a drug used to help patients gain weight after injury, chronic infection, or severe illness. It belongs to the family of drugs called anabolic steroids.


Brands
Adult Dose
Dose: 2.5 to 20 mg
Single Dose: 11 (11.25)
Frequency: As recommended.
Route: PO
Instructions: Given in 2-4 divided doses.
Neonatal
Paedriatic
Characteristics
. The Molecular Weight of Oxandrolone is 306.40.
Contraindications
Oxandrolone is contraindicated in conditions like Hypercalcaemia,Pregnancy,Neoplasms,Prostate cancer.
Effects
The severe or irreversible adverse effects of Oxandrolone, which give rise to further complications include Cholestatic jaundice, Gynacomastia, Testicular atrophy, Hirsutism.The signs and symptoms that are produced after the acute overdosage of Oxandrolone include Depression, Insomnia, Clitoral enlargment.
Indications
Oxandrolone is primarily indicated in conditions like Cachexia, Growth weakness, Osteoporosis, Turners syndrome.
Interactions
No data regarding the interactions of Oxandrolone was found.
Interfrence
Increases Serum Bilirubin Abnormal LFTs Increased Alkaline Phosphatase High serum calciumLow serum glucose
Risks
Drug should not be given to Pregnant Mothers, patients suffering from Kidney dysfunction, patients suffering from Liver Malfunction, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
Tablets Store Between 20°C-25°C. Protect from Sunlight, Moisture and Heat.
Warnings
In children, androgen therapy may accelerate bone maturation without producing compensatory gain in linear growth. This adverse effect results in compromised adult height. The younger the child, the greater the risk of compromising final mature height. The effect on bone maturation should be monitored by assessing bone age of the left wrist and hand every 6 months. Cholestatic hepatitis and jaundice may occur with 17-alpha-alkylated androgens at a relatively low dose. If cholestatic hepatitis with jaundice appears or if liver function tests become abnormal, oxandrolone should be discontinued and the etiology should be determined. Drug-induced jaundice is reversible when the medication is discontinued. In patients with breast cancer, anabolic steroid therapy may cause hypercalcemia by stimulating osteolysis. Oxandrolone therapy should be discontinued if hypercalcemia occurs.
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