Ornidazole

Ornidazole is a nitroimidazole antiprotozoal agent used in ameba and trichomonas infections. It is partially plasma-bound and also has radiation-sensitizing action.


Brands
Adult Dose
Dose: 1.5 gm
Single Dose: 1.5 (1.5)
Frequency: As recommended.
Route: PO
Instructions: For the treatment of Amoebic dysentery once daily for 3 days.
Neonatal
Paedriatic
Dose: 10 mg/kg
Single Dose: 10 (10)
Frequency: 12 hourly
Route: I/V
Instructions: For 5 to 10 days
Characteristics
belongs to Nitroimidazole. . The Molecular Weight of Ornidazole is 219.60.
Contraindications
Ornidazole is contraindicated in conditions like Hypersensitivity to the drug.
Effects
The signs and symptoms that are produced after the acute overdosage of Ornidazole include Nausea, fatigue, Headache, Rashes, Vertigo, Insomnia, Pyrosis.The symptomatic adverse reactions produced by Ornidazole are more or less tolerable and if they become severe, they can be treated symptomatically, these include Weakness, Dizziness, Headache, Ataxia, Nausea, Skin rashes, Urticaria, Skin rashes, dizziness, Ataxia, Weakness.
Indications
Ornidazole is primarily indicated in conditions like Amebiasis, Amoebic dysentry, Bacterial vaginosis, Giardiasis, Trichomoniasis.
Interactions
No data regarding the interactions of Ornidazole was found.
Interfrence
Risks
Drug should not be given to Paediatrics, Pregnant Mothers, and Geriatrics.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
Tablets Protect from Sunlight, Moisture and Heat.
Warnings
Special precautions are required in case of ataxia, vertigo, mental confusion and patients with neurological diseases. There is need for adjustment of dosage and dosage interval in patients with hepatic impairment. Modification of the usual dosage is not necessary in patients of renal failure however, additional post haemodialysis dose may be required in patients undergoing this procedure.
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