Dose: 20 mg/day
Single Dose: 20 (20)
Frequency: As recommended.
Route: PO
Instructions:

. The Molecular Weight of Nitrendipine is 360.40.

Nitrendipine is contraindicated in conditions like Hypotension,Aortic stenosis,Hypersensitivity to any component of product.

The signs and symptoms that are produced after the acute overdosage of Nitrendipine include Bradycardia, Confusion, Hyperglycemia, myocardial depression.The symptomatic adverse reactions produced by Nitrendipine are more or less tolerable and if they become severe, they can be treated symptomatically, these include Dizziness, Headache, Fatigue, Nausea, Palpitation, Flushing, Edema, Gingival hyperplasia, vasodialation.

Nitrendipine is primarily indicated in conditions like Mild to moderate hypertension.

Nitrendipine is known to interact with other drugs, the details of drug interactions is as follows:DrugDetailsSeverityOnsetManagementAminoglutethimideAminoglutethimide may decrease the levels/effects of nitrendipine.CarbamazepineCarbamazepine may decrease the levels/effects of nitrendipine.ClarithromycinMay increase the levels/effects of nitrendipineDiclofenac (K)May increase the levels/effects of nitrendipineDiclofenac (Na)May increase the levels/effects of nitrendipine.Diclofenac DiethylammoniumMay increase the levels/effects of nitrendipine.Diclofenac Free AcidMay increase the levels/effects of nitrendipineDigoxinAt nitrendipine doses exceeding 20 mg/day, increased digoxin levels and toxicity can occur. ErythromycinMay increase the levels/effects of nitrendipine.Nefazodone (HCl)May increase the levels/effects of nitrendipine.NevirapineNevirapine may decrease the levels/effects of nitrendipine.NicardipineMay increase the levels/effects of nitrendipine.Phenytoin (Na)Phenytoin (Na) may decrease the levels/effects of nitrendipine.QuinidineMay increase the levels/effects of nitrendipine.SildenafilBlood pressure-lowering effects may be additive.TadalafilBlood pressure-lowering effects may be additiveVerapamil (HCl)May increase the levels/effects of nitrendipine.VORICONAZOLEVoriconazole may increase the serum concentration of nitrendipine by decreasing its metabolism. Monitor for changes in the therapeutic and adverse effects These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.

'Reduce dosage in elderly; use with caution in patients with liver insufficiency, digital ischemia, nonobstructive hypertrophic cardiomyopathy, Duchenne muscular dystrophy, or in combination with beta-blocking agents. Blood pressure lowering must be done at a rate appropriate for the patient''s clinical condition.'