Nimorazole

Nimorazole is a 5-nitroimidazole derivative. It has antimicrobial actions and uses similar to those of metronidazole.


Brands
Adult Dose
Dose: 250 mg
Single Dose: 250 (250)
Frequency: As recommended.
Route: PO
Instructions: For the treatment of trichomoniasis 3 times daily for 5-7 days.
Neonatal
Paedriatic
Characteristics
belongs to Nitroimidazole. . The Molecular Weight of Nimorazole is 226.20.
Contraindications
Nimorazole is contraindicated in conditions like Liver diseases,Hypersensitivity,Pregnancy,Kidney disease,Breast feeding.
Effects
The signs and symptoms that are produced after the acute overdosage of Nimorazole include Convulsions, Seizures, Leucopenia, Peripheral neuropathy.The symptomatic adverse reactions produced by Nimorazole are more or less tolerable and if they become severe, they can be treated symptomatically, these include Dizziness, Drowsiness, Ataxia, Diarrhea, Insomnia, Skin rashes, Pain, Allergic reactions, Itching, Nausea and vomiting, Heart burn.
Indications
Nimorazole is primarily indicated in conditions like Amoebiasis, Giardiasis, Trichomoniasis, and can also be given in adjunctive therapy as an alternative drug of choice in Gingivitis.
Interactions
No data regarding the interactions of Nimorazole was found.
Interfrence
Risks
Drug should not be given to Pregnant Mothers, patients suffering from Liver Malfunction, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
Warnings
During treatment is not recommended to drink alcoholic beverages. Peripheral neuropathy, transient epileptiform seizures, and leucopenia have sometimes been associated with prolonged or intensive treatment with Nimorazole. Clinical and laboratory monitoring is advised in patients receiving Nimorazole for more than 10 days. Doses should be reduced in patients with severe hepatic impairment. It is suggested that the use of Nimorazole should be avoided during pregnancy, and this caution applies especially to use during the first trimester and to the use of high-dose regimens.
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