NAPADOC PANOBAM CODACET PARACODEINE PCODINE FEMIDOL PLUS TOCOR FORTE DEKOF CODAMIN-P EUPYRIN DERMAAN DERMAAN FEBRICOD FEBRICOD FEBRICOD FEBRICOD FEBRICOD FEBRICOD FEBRICOD C TEMPOL-C VIODOL CD CODOGESIC PAINEZE CODAR PARACOD HYCODINE CODEINE PLUS SYNADOC BRUFEN PLUS DANCIN DANCIN OPAGESIC OPAGESIC OPAGESIC

Dose: 10 to 50 mg
Single Dose: 30 (30)
Frequency: 6 hourly
Route: PO
Instructions:

Dose: 250 ug/kg
Single Dose: 250 (250)
Frequency: 6 hourly
Route: Oral
Instructions: -

Codeine (Phosphate) is the derivative of Codeine. It is of Semi Synthetic origin and belongs to Opioid. It belongs to OPIATE agonist pharmacological group on the basis of mechanism of action and also classified in Analgesic pharmacological group.The Molecular Weight of Codeine is 406.40. It is weakly acidic drug, 7.29% solution of the drug is isotonic and Its pKa is 8.2.

Codeine is contraindicated in conditions like Asthma,Respiratory depression,Raised intracranial pressure.

The severe or irreversible adverse effects of Codeine, which give rise to further complications include Hallucinations.Codeine produces potentially life-threatening effects which include Respiratory depression. which are responsible for the discontinuation of Codeine therapy.The signs and symptoms that are produced after the acute overdosage of Codeine include Hypotension, Convulsions, Respiratory depression, Deepening coma, Circulatory failure.The symptomatic adverse reactions produced by Codeine are more or less tolerable and if they become severe, they can be treated symptomatically, these include Vertigo, Nausea, Vomiting, Palpitation, Constipation, Dry mouth, Bradycardia, Facial flushing, SweatingX, Miosis, Ureteric spasm, Biliary spasm, Mood changes.

Codeine is primarily indicated in conditions like Cough, Diarrhoea, Mild to moderate pain, and can also be given in adjunctive therapy as an alternative drug of choice in Anxiety, Control of agitated states in elderly without confusion.

Codeine is known to interact with other drugs, the details of drug interactions is as follows:DrugDetailsSeverityOnsetManagementAlcoholMoclobemideNefopam (HCl)ParoxetinePericyazineThese drugs shouldnot be taken concurrently without doctors prescription. These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

Tests for the estimation of Alkaloids, Morphine and Barbiturates in urine.

Drug should not be given to Paediatrics, Pregnant Mothers, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.

Inj Store at room temperature. Do not Freeze. Protect from Sunlight. Tab, Oral Soln Store Below 40°C. Protect from Sunlight and Moisture.

Codeine phosphate should be used with caution, and reduced the initial dose in patients with acute abdominal conditions, convulsive disorders, kidney or liver impairment, fever, hypothyroidism, in patients with recent gastrointestinal or urinary tract surgery. It should be used with caution in very young or elderly patients.