Lopinovir

Lopinovir is a protease inhibitor with antiviral activity against HIV.


Brands
Adult Dose
Dose: 400 mg
Single Dose: 400 (400)
Frequency: As recommended.
Route: oral
Instructions:
Neonatal
Paedriatic
Dose:
Single Dose:
Frequency:
Route:
Instructions:
Characteristics
. The Molecular Weight of Lopinovir is 444.44.
Contraindications
Lopinovir is contraindicated in conditions like Hypersensitivity.
Effects
The signs and symptoms that are produced after the acute overdosage of Lopinovir include Pancreatitis.The symptomatic adverse reactions produced by Lopinovir are more or less tolerable and if they become severe, they can be treated symptomatically, these include Hypercholesterolemia.
Indications
Lopinovir is primarily indicated in conditions like Rocky mountain spotted fever, Trachoma, Urinary tract infection.
Interactions
Lopinovir is known to interact with other drugs, the details of drug interactions is as follows:DrugDetailsSeverityOnsetManagementAbacavirRosuvastatinLopinovir significantly increased rosuvastatin exposure. Iin patients taking a combination of lopinavir, the dose of Rosuvastatin should be limited to 10 mg once daily. Tenofovir DisoproxilLopinavir has been shown to increase tenofovir concentrations.VORICONAZOLELopinavir may reduce serum concentration and efficacy of voriconazole. This combination should be avoided Vortioxetineincreases the level of vortioxetineuse alternative or decrease dose of vortioxetine by 50% These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Interfrence
Risks
Drug should not be given to Paediatrics, Pregnant Mothers, and patients suffering from Liver Malfunction.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
Warnings
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