ZELDOX ZELDOX ZAPRIS ZAPRIS ZAPRIS ZAPRIS ZAPRIS ZAPRIS ZAPRIS ZAPRIS ZIPRA ZIPRA ZIPONE PRAZIP PRAZIP PRAZIP PRAZIP ZIMMOR ZIP ZIP ZIP ZIPRASCOT ZIPRASCOT ZEPRIS ZEPRIS ZEPRIS ZEPRIS ZEPRIS ZIPRONE ZIPRONE ZIPRONE ZIPRONE ZIP ONE ZIP ONE ZIPADONE ZIPADONE ZIPRAWIN ZIPRAWIN ZIPRAWIN ZIPRAWIN ZIPRAWIN ZIPRAWIN ZIPROX ZIPROX ZIPROX ZIPROX ZIPROX XEPEX XEPEX SYCOZIP ZIPSYDE

Dose: 10 to 40 mg
Single Dose: 25 (25)
Frequency: 12 hourly
Route: IM
Instructions: Patient sholud switch therapy as soon as possible.

. The Molecular Weight of Ziprasidone is 412.94.

Ziprasidone is contraindicated in conditions like Cardiac arrhythmia,QTc prolongation,Hypersensitivity reactions.

The severe or irreversible adverse effects of Ziprasidone, which give rise to further complications include Rashes, Fever, Muscle twitching, QT prolongation.Ziprasidone produces potentially life-threatening effects which include Seizures. which are responsible for the discontinuation of Ziprasidone therapy.The signs and symptoms that are produced after the acute overdosage of Ziprasidone include Constipation, Dyspepsia, Sedation, Somnolence.The symptomatic adverse reactions produced by Ziprasidone are more or less tolerable and if they become severe, they can be treated symptomatically, these include Dizziness, Headache, Nausea, Anxiety, Confusion, Somnolence, Sneezing, Sexual dysfunction, Obesity, Agitation, Blood dyscrasias, Cholestatic Jaundice, Orthostatic hypotension, Hypertension, Hyperlipidemia, GI disturbance, Hepatitis, Hyperglycemia, Hyperprolactinemia, Tardive dyskinesia, Extra pyramidal symptoms, Seizures.

'Ziprasidone is primarily indicated in conditions like Schizophrenia, and can also be given in adjunctive therapy as an alternative drug of choice in Depression, Mania, Tourette''s syndrome.'

Ziprasidone is known to interact with other drugs, the details of drug interactions is as follows:DrugDetailsSeverityOnsetManagementClarithromycinConcomitant use of ziprasidone and clarithromycin increases the risk of QT prolongation.DroperidolContinue on sepertepsIsoniazidLiver enzyme inhibitors (e.g isoniazid) decreases the metabolism of ziprasidone.LevodopaZiprasidone antagonizes the effect of Levodopa and Dopamine agonists.RifampicinLiver enzyme inducers (e.g rifampicin) accelerates the metabolism of ziprasidone.VORICONAZOLEAdditive QTc-prolonging effects may increase the risk of severe arrhythmias. Concomitant therapy should be avoided These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

Drug should not be given to Cardiac / Hypertensive Patients.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.

Store in a well closed container. Protect from Moisture and Heat.

Ziprasidone should be avoided in combination with other drugs that are known to prolong QTc interval.Avoid use of alcohol.Avoid activities involving high temperature. It should not be used in patients with a history of seizures and cerebrovascular disease.