Dose: 3 to 4.5 g
Single Dose: 3.8 (3.75)
Frequency: As recommended.
Route: oral
Instructions:

belongs to flourinated pyramadine. . The Molecular Weight of Floxuridine is 246.19. Its pKa is 7.44.

Floxuridine is contraindicated in conditions like Infections,Myelosuppression,Nutrition deficiency.

The severe or irreversible adverse effects of Floxuridine, which give rise to further complications include Allergic reactions, Bleeding, Fatigue.Floxuridine produces potentially life-threatening effects which include Cirrhosis of the liver. which are responsible for the discontinuation of Floxuridine therapy.The signs and symptoms that are produced after the acute overdosage of Floxuridine include Diarrhea.The symptomatic adverse reactions produced by Floxuridine are more or less tolerable and if they become severe, they can be treated symptomatically, these include Rashes, Stomatitis, Erythema, Itching, Nausea and vomiting, stomach cramping, Stomach cramping, Myocardial Ischemia.

Floxuridine is primarily indicated in conditions like Colorectal cancer, Gastrointestinal stromal tumour, Neoplasms.

Floxuridine is known to interact with other drugs, the details of drug interactions is as follows:DrugDetailsSeverityOnsetManagementTorasemideFloxuridine, a strong CYP2C9 inhibitor, may increase the serum concentration of Torasemide, a CYP2C9 substrate, by decreasing Torasemide metabolism and clearance. Consider alternate therapy or monitor for changes in the therapeutic and adverse effects of Torasemide if Floxuridine is initiated, discontinued or dose changed.VORICONAZOLEFloxuridine may increase the serum concentration of voriconazole by decreasing its metabolism. Monitor for changes in the therapeutic and adverse effects of voriconazole if floxuridine is initiated, discontinued or dose changed. These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

Periodic blood countIncreased Serum Alkaline PhosphataseInterferes with BSP, prothrombin & sedimentation rate assays, Thromp openia

Drug should not be given to Pregnant Mothers, patients suffering from Kidney dysfunction, patients suffering from Liver Malfunction, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.

Protect from Sunlight.

Floxuridine should not be given to allergic patients. Floxuridine should be given only under the supervision of qualified doctor experienced in cancer chemotherapy. Due to severe toxic effects all patients should be hospitalized for initial course of therapy. aoid contact with people having cold,fluor any contageous illness and also who have been vaccinated with live vaccine recently. Should be used with caution in impaired Kidney & renal function