Quinestrol

Quinestrol is synthetic origin used in hormone replacement therapy and occassionally to treat breast cancer and prostate cancer.


Brands
Adult Dose
Dose: PO
Single Dose:
Frequency:
Route:
Instructions:
Neonatal
Paedriatic
Characteristics
. It is of Synthetic origin and belongs to Oestrogen. . The Molecular Weight of Quinestrol is 364.52.
Contraindications
Quinestrol is contraindicated in conditions like Vaginal bleeding,Pregnancy,Porphyria.
Effects
The severe or irreversible adverse effects of Quinestrol, which give rise to further complications include Systemic lupus erythematosus.Quinestrol produces potentially life-threatening effects which include Venous thromboembolism. which are responsible for the discontinuation of Quinestrol therapy.The signs and symptoms that are produced after the acute overdosage of Quinestrol include Shortness of breadth, Vaginal bleeding.The symptomatic adverse reactions produced by Quinestrol are more or less tolerable and if they become severe, they can be treated symptomatically, these include Dizziness, Weight gain, Nausea and vomiting, Fluid retention, Bloated feeling.
Indications
Quinestrol is primarily indicated in conditions like Hormone replacement therapy, Menopausal flushing, and can also be given in adjunctive therapy as an alternative drug of choice in Breast cancer, Prostate cancer.
Interactions
No data regarding the interactions of Quinestrol was found.
Interfrence
Risks
Drug should not be given to Pregnant Mothers.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
Store at room temperature. Protect from Sunlight, Moisture and Heat.
Warnings
It should not be given to the patients with active thrombophlebitis or thromboembolic disease, abnormal vaginal bleeding, women with antiphospholipid antibodies, history of endometriosis. when used as HRT, it should be used with caution in diseases which may be excerbated during pregnancy or quinestrol therapy including diabetes, asthma, epilepsy, hypertension, cardiac or renal disease, sickle cell anemia, multiple sclerosis and cholera. It should not be used during lactation.
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