Dose: 10 to 16 mg
Single Dose: 13 (13)
Frequency: As recommended.
Route: oral
Instructions:

Estramustine also known as Estramustine Sodium Phosphate, Estramustine Sodium Phosphate, Estramustine Sodium Phosphate. . It is of Synthetic origin and belongs to Estrogen. . The Molecular Weight of Estramustine is 440.40.

Estramustine is contraindicated in conditions like Thrombophlebitis,Thrombo-embolic complications,Hypersensitivity to any component of product.

The severe or irreversible adverse effects of Estramustine, which give rise to further complications include Thrombocytopenia, Confusion, Chest pain, Hepatic dysfunction.Estramustine produces potentially life-threatening effects which include Hypertension, Thromboembolism, Leukopenia. which are responsible for the discontinuation of Estramustine therapy.The symptomatic adverse reactions produced by Estramustine are more or less tolerable and if they become severe, they can be treated symptomatically, these include Tiredness, Nausea, Rashes, Itching, Loss of libido, Loss of appetite.

Estramustine is primarily indicated in conditions like Palliative surgery., Prostate cancer, and can also be given in adjunctive therapy as an alternative drug of choice in Metastatic, Prostatic cancer.

Estramustine is known to interact with other drugs, the details of drug interactions is as follows:DrugDetailsSeverityOnsetManagementClodronate These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

Abnormal LFTs

If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.

Drug Form Store at room temperature, or in refrigerator. Use within 2 - 8 C if refrigerated and within 24-28 if kept at room temperature.

Should be used with caution in patients with the history of thrombophlebitis, thrombosis, thromboembolicn disorders. Because hypertension may occur bloodpressure should be monitored periodically. Patients with prostate cancer and osteoblastic metastases are at risk for hypocalcemia and should have calcium levels closely monitored.