Enalaprilat

Enalaprilat is the first dicarboxylate containing ACE inhibitor,developed partially to overcome limitations of captopril.It works by helping to relax blood vessels and thus helps in reducing blood pressure.

Brands
Adult Dose
Dose: 10 to 20 mg
Single Dose: 15 (15)
Frequency: As recommended.
Route: oral
Instructions:
Neonatal
Paedriatic
Characteristics
. The Molecular Weight of Enalaprilat is 384.40.
Contraindications
Enalaprilat is contraindicated in conditions like Pregnancy.
Effects
The signs and symptoms that are produced after the acute overdosage of Enalaprilat include fatigue, Dizziness, Headache, Dry cough, Deafness.The symptomatic adverse reactions produced by Enalaprilat are more or less tolerable and if they become severe, they can be treated symptomatically, these include Rashes, Itching, Hypotension, Loss of taste.
Indications
Enalaprilat is primarily indicated in conditions like Hypertension, Left ventricular dysfunction, and can also be given in adjunctive therapy as an alternative drug of choice in Heart failure.
Interactions
No data regarding the interactions of Enalaprilat was found.
Interfrence
Liver Function Test (LFT) Increased in serum creatinin
Risks
Drug should not be given to Pregnant Mothers.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
Store in a well closed container, Below 30°C.
Warnings
Precautions should be considered in patients with aortic stenosis or outflow tract obstruction. In patients with renovascular diseases.
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