Chloroprocaine

Chloroprocaine is an anesthetic agent indicated for production of local or regional anesthesia, particularly for oral surgery. Chloroprocaine (like cocaine) has the advantage of constricting blood vessels which reduces bleeding, unlike other local anesthetics like lidocaine.


Brands
Adult Dose
Dose: 11 mg/kg
Single Dose: 11 (11)
Frequency: 24 hourly
Route: IV
Instructions: With epinephrine.. Not to exceed t max total dose of 800mg.
Neonatal
Paedriatic
Characteristics
.
Contraindications
Chloroprocaine is contraindicated in conditions like Neurological disorders,Hypersensitivity to the drug.
Effects
The severe or irreversible adverse effects of Chloroprocaine, which give rise to further complications include Convulsions, CNS stimulation.Chloroprocaine produces potentially life-threatening effects which include change in cardiac conduction. which are responsible for the discontinuation of Chloroprocaine therapy.The signs and symptoms that are produced after the acute overdosage of Chloroprocaine include Bradycardia, Hypotension, Cardiac arrest, Ventricular arrhythmias, myocardial depression.The symptomatic adverse reactions produced by Chloroprocaine are more or less tolerable and if they become severe, they can be treated symptomatically, these include Drowsiness, Fever, Tinnitus, Blurred vision, Itching.
Indications
Chloroprocaine is primarily indicated in conditions like Anesthesia, Nerve block, and can also be given in adjunctive therapy as an alternative drug of choice in Analgesic.
Interactions
No data regarding the interactions of Chloroprocaine was found.
Interfrence
Risks
If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
Inj, sol Store in a well closed container, at room temperature, Between 15°C-30°C. Do not Freeze. Protect from Sunlight, Moisture and Heat.
Warnings
The safety and effective use of chloroprocaine depend on proper dosage, correct technique, adequate precautions and readiness for emergencies. Injections should be made slowly, with frequent aspirations before and during the injection to avoid intravascular injection. Local anesthetic injections containing a vasoconstrictor should be used cautiously and in carefully circumscribed quantities in areas of the body supplied by end arteries or having otherwise compromised blood supply. Local anesthetics should also be used with caution in patients with impaired cardiovascular function since they may be less able to compensate for functional changes associated with the prolongation of A-V conduction produced by these drugs. Chloroprocaine should be given to a pregnant woman only if clearly needed.
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