Methoxyflurane

Methoxyflurane is a general inhalation anesthetic used for the induction and maintainence of general anesthesia.It induces muscle relaxation and reduces pain sensitivity by altering tissues excitibilty.It does so by decreasing the extent of gap junction mediated cell-cell coupling and altering the activity of the channels.

Brands
Adult Dose
Dose: 6 ml
Single Dose: 6 (6)
Frequency: As recommended.
Route:
Instructions:
Neonatal
Paedriatic
Characteristics
. It is of Synthetic origin and belongs to Fluronated hydrocarbon. . The Molecular Weight of methoxyflurane is 165.00.
Contraindications
methoxyflurane is contraindicated in conditions like Respiratory depression,Cardiovascular disease,Unconciousness,Hypersensitivity,Head injury.
Effects
The severe or irreversible adverse effects of methoxyflurane, which give rise to further complications include Nephrotoxicity, Renal failure, Increased serum creatinine, Laryngospasm, Oxaluria.The signs and symptoms that are produced after the acute overdosage of methoxyflurane include Bradycardia, Hypotension, Respiratory depression, Cardiac arrest.The symptomatic adverse reactions produced by methoxyflurane are more or less tolerable and if they become severe, they can be treated symptomatically, these include Dizziness, Drowsiness, Nausea, Vomiting, Fever, Coughing, Polyuria, dizziness.
Indications
methoxyflurane is primarily indicated in conditions like Labor pains, Pain in short surgical procedure., Trauma.
Interactions
No data regarding the interactions of methoxyflurane was found.
Interfrence
Risks
Drug should not be given to Pregnant Mothers, Cardiac / Hypertensive Patients, patients suffering from Kidney dysfunction, and patients suffering from Liver Malfunction.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
Store in a well closed container, Below 40°C. Do not Freeze. Protect from Sunlight.
Warnings
Caution should be exercised in the following circumstances due to the possibility of increased free flouride and oxalic acid levels .1.Reduced GFR or urine output.2.Reduced renal blood flow.
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